Molecular breeding of polymerases for amplification of ancient DNA
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DNA polymerases as useful reagents for biotechnology - the history of developmental research in the fieldAncient genomicsLearning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylasesDetection of DNA sequences refractory to PCR amplification using a biophysical SERRS assay (Surface Enhanced Resonant Raman Spectroscopy)DNA polymerases engineered by directed evolution to incorporate non-standard nucleotidesRoad blocks on paleogenomes--polymerase extension profiling reveals the frequency of blocking lesions in ancient DNAMicrofluidic systems for biosensingNew insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology.CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.Molecular breeding of polymerases for resistance to environmental inhibitors.SeSaM-Tv-II generates a protein sequence space that is unobtainable by epPCR.Mutant Taq DNA polymerases with improved elongation ability as a useful reagent for genetic engineering.Enzyme-free detection and quantification of double-stranded nucleic acids.Screening mutant libraries of T7 RNA polymerase for candidates with increased acceptance of 2'-modified nucleotides.Directed evolution of DNA polymerases: construction and screening of DNA polymerase mutant libraries.A high-throughput screening method to reengineer DNA polymerases for random mutagenesis.Systematic evaluation of bias in microbial community profiles induced by whole genome amplification.Reconstructing ancient genomes and epigenomes.DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity.In vitro evolution of phi29 DNA polymerase using isothermal compartmentalized self replication technique.Screening through the PLICable promoter toolbox enhances protein production in Escherichia coli.Human evolution: a tale from ancient genomes.Directed polymerase evolution.Click nucleic acid ligation: applications in biology and nanotechnology.Methods for the directed evolution of proteins.A triazole linkage that mimics the DNA phosphodiester group in living systems.A polymerase engineered for bisulfite sequencing.Historical records from dated sediment cores reveal the multidecadal dynamic of the toxic dinoflagellate Alexandrium minutum in the Bay of Brest (France).Evolving a polymerase for hydrophobic base analogues.Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering.Compartmentalized self-replication under fast PCR cycling conditions yields Taq DNA polymerase mutants with increased DNA-binding affinity and blood resistance.Synthetic polymers and their potential as genetic materials.Compartmentalized partnered replication for the directed evolution of genetic parts and circuits.Design and Discovery of New Combinations of Mutant DNA Polymerases and Modified DNA Substrates.A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets.Effects of nutrients and warming onPlanktothrixdynamics and diversity: a palaeolimnological view based on sedimentary DNA and RNAAncient DNA for the Archaeologist: The Future of African Research
P2860
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P2860
Molecular breeding of polymerases for amplification of ancient DNA
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Molecular breeding of polymerases for amplification of ancient DNA
@ast
Molecular breeding of polymerases for amplification of ancient DNA
@en
Molecular breeding of polymerases for amplification of ancient DNA
@nl
type
label
Molecular breeding of polymerases for amplification of ancient DNA
@ast
Molecular breeding of polymerases for amplification of ancient DNA
@en
Molecular breeding of polymerases for amplification of ancient DNA
@nl
prefLabel
Molecular breeding of polymerases for amplification of ancient DNA
@ast
Molecular breeding of polymerases for amplification of ancient DNA
@en
Molecular breeding of polymerases for amplification of ancient DNA
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Molecular breeding of polymerases for amplification of ancient DNA
@en
P2093
David Loakes
Didier Gasparutto
Jean Cadet
Marc d'Abbadie
Philipp Holliger
Roger Woodgate
P2860
P2888
P304
P356
10.1038/NBT1321
P407
P577
2007-08-01T00:00:00Z