Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)
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Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial CellsDevelopment of Burkholderia mallei and pseudomallei vaccinesGlyburide reduces bacterial dissemination in a mouse model of melioidosisPost-exposure therapeutic efficacy of COX-2 inhibition against Burkholderia pseudomalleiThe urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferiToll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis.The role of NOD2 in murine and human melioidosisActivation of Toll-like receptors by Burkholderia pseudomallei.MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomalleiExpression and function of macrophage migration inhibitory factor (MIF) in melioidosis.Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis).A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis.Genome wide transcriptome profiling of a murine acute melioidosis model reveals new insights into how Burkholderia pseudomallei overcomes host innate immunityThe Burkholderia pseudomallei type III secretion system and BopA are required for evasion of LC3-associated phagocytosisThe genetic and molecular basis of O-antigenic diversity in Burkholderia pseudomallei lipopolysaccharide.Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).Divergent functions of Toll-like receptors during bacterial lung infections.Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis).Development of vaccines against burkholderia pseudomallei.NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.Burkholderia pseudomallei-induced expression of a negative regulator, sterile-alpha and Armadillo motif-containing protein, in mouse macrophages: a possible mechanism for suppression of the MyD88-independent pathway.MyD88-dependent recruitment of monocytes and dendritic cells required for protection from pulmonary Burkholderia mallei infection.T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients.Characterization of the murine macrophage response to infection with virulent and avirulent Burkholderia species.Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models.The Role of TLR2 in Infection and ImmunityBurkholderia pseudomallei triggers altered inflammatory profiles in a whole-blood model of type 2 diabetes-melioidosis comorbidityTriggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental MelioidosisToll-Like Receptor Signalling Is Not Involved in Platelet Response to Streptococcus pneumoniae In Vitro or In Vivo.The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human DiseaseThe gut microbiota as a modulator of innate immunity during melioidosisBacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling.Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis)Host gene expression analysis in Sri Lankan melioidosis patients.Sensing gram-negative bacterial lipopolysaccharides: a human disease determinant?Impaired TLR5 functionality is associated with survival in melioidosisBurkholderia pseudomallei Capsule Exacerbates Respiratory Melioidosis but Does Not Afford Protection against Antimicrobial Signaling or Bacterial Killing in Human Olfactory Ensheathing Cells.
P2860
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P2860
Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@ast
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@en
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@nl
type
label
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@ast
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@en
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@nl
prefLabel
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@ast
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@en
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Toll-like receptor 2 impairs h ...... ria pseudomallei (Melioidosis)
@en
P2093
Alex F de Vos
Catharina W Wieland
Mark C Dessing
Masja Leendertse
Narisara Chantratita
Nicholas White
W Joost Wiersinga
Wirongrong Chierakul
P2860
P3181
P356
10.1371/JOURNAL.PMED.0040248
P407
P50
P577
2007-07-31T00:00:00Z