about
Accessing Nature's diversity through metabolic engineering and synthetic biologySystems Biology Approaches to Understand Natural Products BiosynthesisPredominately Uncultured Microbes as Sources of Bioactive AgentsPhylogenomic Analysis of Natural Products Biosynthetic Gene Clusters Allows Discovery of Arseno-Organic Metabolites in Model StreptomycetesThe multi-omics promise in context: from sequence to microbial isolateDereplication of peptidic natural products through database search of mass spectra.Natural products as mediators of disease.Using natural products for drug discovery: the impact of the genomics era.Natural product discovery from the human microbiome.Microbial metabolites in health and disease: Navigating the unknown in search of function.Homeostatic Immunity and the Microbiota.plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clustersDigitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae.Characterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: generation of a novel improved derivativeMetabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid MonomerComputational genomic identification and functional reconstitution of plant natural product biosynthetic pathways.IMG-ABC: new features for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery in thousands of microbial genomes.The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters.Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species.Antibiotics v2.0: computational and synthetic biology approaches to combat antibiotic resistance.Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea.The regulatory mechanism underlying light-inducible production of carotenoids in nonphototrophic bacteria.SBSPKSv2: structure-based sequence analysis of polyketide synthases and non-ribosomal peptide synthetases.Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites.Biogenesis of antibiotics-viewing its history and glimpses of the future.Mining prokaryotes for antimicrobial compounds: from diversity to function.The evolution of genome mining in microbes - a review.Specialised metabolites regulating antibiotic biosynthesis in Streptomyces spp.Toolbox for Antibiotics Discovery from Microorganisms.Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.Ribosomally synthesized and post-translationally modified peptide natural product discovery in the genomic era.Non-ribosomal peptide synthetases: Identifying the cryptic gene clusters and decoding the natural product.Mining Bacterial Genomes for Secondary Metabolite Gene Clusters.Endophytic actinobacteria: Diversity, secondary metabolism and mechanisms to unsilence biosynthetic gene clusters.Bioinformatics tools for the identification of gene clusters that biosynthesize specialized metabolites.Symbiosis-inspired approaches to antibiotic discovery.Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens.Function-related replacement of bacterial siderophore pathways.Opportunities for natural products in 21st century antibiotic discovery.antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.
P2860
Q26747738-6A01289B-384F-4B98-90E0-44A3A36F2CAFQ26772223-52800782-DD41-4DBA-8FB5-21B3CD22A9B6Q28073712-7C8A73F8-C8DE-49E8-AC40-236E313E71FAQ28830295-9EEB4C88-8662-48EC-82FB-8048BEF63D9AQ30224335-E3F8F10D-AC6B-4D75-80D9-D9892B4FFE58Q33614929-303C143D-8D11-4E25-ADB1-2D7AAF08AAA3Q36200942-048E64B8-CE2B-43F1-8060-1BCAF6C99E39Q36302104-D26DF60B-22C1-426E-8368-216D93171F9EQ36340566-FBB2BAFC-B84C-4464-A311-F0AA36D0ABDFQ36340571-5285E616-CA57-4748-8B19-227D624DF192Q36351062-0645817F-604A-4A22-83B9-6D619247330AQ36358104-55BB062C-B176-43D9-9255-EAC3BF638384Q36368545-6343A8F5-4DE3-4E93-9E7A-7FBFBAA34924Q36606532-6BF5BB55-AFEF-45C7-A29E-D787B944ADBDQ36787154-8E0C1194-D5C3-4152-ACA0-85663B5C28F6Q37181634-27E39CF1-CD85-43BA-A06F-405A31EB0358Q37556849-4C5B78D6-D7CA-4DCC-98D7-F6758B066B25Q37557065-2B63AEE9-D5C1-4872-B5B8-B0E42558FCFFQ38371710-8AF744BE-2335-454A-8C07-35FF83A4EC9AQ38746703-51124E0C-E9CB-40CD-8F35-F8BF70A988B3Q38749943-152065AD-CE8F-4ABE-A1BB-9674F4331021Q38769971-9B125088-9325-4751-A0D5-8665DD37668EQ38810972-13368859-2652-48E3-94AA-EA27804426CDQ38823592-0465BEE6-D078-4C60-8006-E7E8C4C0C597Q38836571-2609225C-E140-48AF-8C69-22A8DA774E75Q38840658-A16D27F6-17E7-4F5B-A0CF-C30571FEB666Q38858040-AC2DF639-0AF2-44CB-AC18-F7582447D1E4Q38861928-53AA4CAF-0CEB-45D2-945E-1A50F9162061Q38867326-622953EE-5D7C-4294-8E64-334F528AFBD5Q38916352-49136429-E9AC-4061-B34B-CF5620C869BCQ38928841-406C906C-2345-45BB-8A24-599839F46495Q38946726-C0947983-EE4C-4905-9E4D-10402EC91F4CQ39165584-F3C2D855-6263-45C0-A423-38EF0734D901Q39208836-6E5ADFFD-0D97-461A-9230-4CB536B12D15Q39234336-6BF38EF5-93DD-475E-B085-1D9B71F96284Q39340574-B5F6462F-7A64-4F43-957A-89D7E0DD27FFQ39392982-5922F26D-9DCD-49DF-B31B-05BA9191AE32Q40092732-8C5D08E6-4B34-4656-8981-8F49F055F147Q40189627-C72024D1-89D9-468C-B005-05A22A6E53B7Q40231155-15428950-DA40-4477-B79B-736DEF559E98
P2860
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Computational approaches to natural product discovery
@ast
Computational approaches to natural product discovery
@en
type
label
Computational approaches to natural product discovery
@ast
Computational approaches to natural product discovery
@en
prefLabel
Computational approaches to natural product discovery
@ast
Computational approaches to natural product discovery
@en
P2860
P3181
P356
P1476
Computational approaches to natural product discovery
@en
P2093
Marnix H Medema
Michael A Fischbach
P2860
P2888
P304
P3181
P356
10.1038/NCHEMBIO.1884
P407
P577
2015-09-01T00:00:00Z