SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway - Test2 - elhamkhani - TriplyDB

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

http://www.wikidata.org/entity/Q28854278

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Diagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review Roles of the canonical myomiRs miR-1, -133 and -206 in cell development and disease MicroRNAs: a new piece in the paediatric cardiovascular disease puzzle MicroRNAs in heart failure: Small molecules with major impact Forkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathy Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle.Serum microRNA-1 and microRNA-133a levels reflect myocardial steatosis in uncomplicated type 2 diabetes Role of microRNA-1 in human cancer and its therapeutic potentials.High-salt intake suppressed microRNA-133a expression in Dahl SS rat myocardium Laser-targeted ablation of the zebrafish embryonic ventricle: a novel model of cardiac injury and repair.Application of time-resolved autofluorescence to label-free in vivo optical mapping of changes in tissue matrix and metabolism associated with myocardial infarction and heart failure.Targeting cardiomyocyte Ca2+ homeostasis in heart failure.Exercise training restores the cardiac microRNA-1 and -214 levels regulating Ca2+ handling after myocardial infarction.Diabetic cardiomyopathy and metabolic remodeling of the heart.Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling.The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy.Alterations in ryanodine receptors and related proteins in heart failure Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function.MicroRNAs in myocardial ischemia: identifying new targets and tools for treating heart disease. New frontiers for miR-medicine.The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy.miRNA-1: functional roles and dysregulation in heart disease.Noncoding RNAs and myocardial fibrosis.The regulation of sarco(endo)plasmic reticulum calcium-ATPases (SERCA).Intercellular communication lessons in heart failure.A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling.microRNAs and Cardiovascular Remodeling.The regulatory function of microRNA-1 in arrhythmias.MicroRNA-1 overexpression blunts cardiomyocyte hypertrophy elicited by thyroid hormone.Does proteasome regulate the level of microRNA-1 in cardiomyocytes? Application to anoxia-reoxygenation.Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats.Emerging molecular therapies targeting myocardial infarction-related arrhythmias.A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair.MicroRNAs in Heart Failure, Cardiac Transplantation, and Myocardial Recovery: Biomarkers with Therapeutic Potential.Circulating microRNA-132 levels improve risk prediction for heart failure hospitalization in patients with chronic heart failure.Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy.Dedifferentiation, Proliferation, and Redifferentiation of Adult Mammalian Cardiomyocytes After Ischemic Injury.The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations.Oleanolic acid alleviated pressure overload-induced cardiac remodeling.

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P2860

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

http://www.wikidata.org/entity/Q28854278

description

2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի մայիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2012

@ast

im Mai 2012 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

wetenschappelijk artikel (gepubliceerd op 2012/05/01)

@nl

наукова стаття, опублікована в травні 2012

@uk

مقالة علمية (نشرت في مايو 2012)

@ar

name

SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

@ast

SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

@en

type

label

SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

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SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

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prefLabel

SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

@ast

SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

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European Heart Journal

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SERCA2a gene therapy restores ...... n Akt/FoxO3A-dependent pathway

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Aanchal Pahuja

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Adam M Mills

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Alexander R Lyon

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Cornelia Geers-Knörr

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Ingo Volkmann

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Julia Bretthauer

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Kenneth T Macleod

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Regalla Kumarswamy

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Roger J Hajjar

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Theresia Kraft

http://www.w3.org/2001/XMLSchema#string

P2860

Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling

MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes

MicroRNA regulation of cell lineages in mouse and human embryonic stem cells

Identification of tissue-specific microRNAs from mouse

miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2

The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes

Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

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1067-1075

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scholarly article

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925544

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10.1093/EURHEARTJ/EHS043

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9

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33

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Sian E. Harding

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2012-02-23T00:00:00Z

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221858812

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22362515

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regulation of calcium ion export from cell

positive regulation of calcium ion export from cell

negative regulation of calcium ion export from cell

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3341631

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