Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
about
Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase IA novel nuclear localization signal in human DNA topoisomerase IThe role of lysine 532 in the catalytic mechanism of human topoisomerase IInhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505Phosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivityInteraction between the N-terminus of human topoisomerase I and SV40 large T antigenInteraction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factorThe tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamilyGranzyme B cleavage of autoantigens in autoimmunityThe inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosisMost nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunityRotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxationNonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analogStructures of Minimal Catalytic Fragments of Topoisomerase V Reveals Conformational Changes Relevant for DNA BindingCaspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosisReplacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistantThe domain organization of human topoisomerase IResidues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitroNatively unfolded proteins: a point where biology waits for physicsThe role of histidine 632 in catalysis by human topoisomerase I.Reversible inhibitors of lambda integrase-mediated recombination efficiently trap Holliday junction intermediates and form the basis of a novel assay for junction resolution.Assembly of the replication initiation complex on SV40 origin DNA.Cellular topoisomerase I modulates origin binding by bovine papillomavirus type 1 E1.Disruption of a DNA topoisomerase I gene affects morphogenesis in Arabidopsis.DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde?Topoisomerase I associates specifically with simian virus 40 large-T-antigen double hexamer-origin complexesA novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex.Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein-DNA binding siteTopoisomerase I inhibition with topotecan: pharmacologic and clinical issues.The C-terminal domain but not the tyrosine 723 of human DNA topoisomerase I active site contributes to kinase activityMutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA.Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1.Human topoisomerase I C-terminal domain fragment containing the active site tyrosine is a molten globule: implication for the formation of competent productive complex.Identification of Leishmania donovani Topoisomerase 1 inhibitors via intuitive scaffold hopping and bioisosteric modification of known Top 1 inhibitorsTopoisomerase assaysTryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removalThe cap region of topoisomerase I binds to sites near both ends of simian virus 40 T antigen.Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase IInduction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells.Role of a tryptophan anchor in human topoisomerase I structure, function and inhibition.
P2860
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P2860
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
description
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
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im März 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 1996/03/29)
@nl
наукова стаття, опублікована в березні 1996
@uk
مقالة علمية (نشرت في 29-3-1996)
@ar
name
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@ast
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@en
type
label
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@ast
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@en
prefLabel
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@ast
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@en
P2093
P2860
P3181
P356
P1476
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
@en
P2093
G. C. Ireton
J. J. Champoux
K. R. Madden
L. H. Parker
L. Stewart
P2860
P304
P3181
P356
10.1074/JBC.271.13.7593
P407
P577
1996-03-29T00:00:00Z