sameAs
Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndromeGuidelines for the use and interpretation of assays for monitoring autophagyCloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family membersIdentification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteinsComparative and demographic analysis of orang-utan genomesGenome analysis of the platypus reveals unique signatures of evolutionGenome sequence of the Brown Norway rat yields insights into mammalian evolutionBiochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzymeGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotesIdentification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeatsIdentification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolaseThe ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathwayADAMTS-12 metalloprotease is necessary for normal inflammatory responseRegulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infectionMatriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteinsCloning and enzymatic analysis of 22 novel human ubiquitin-specific proteasesLoss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in miceCathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal locationIdentification and structural and functional characterization of human enamelysin (MMP-20)Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chainIdentification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distributionBiochemical characterization of human collagenase-3Cloning and expression analysis of a novel human serine hydrolase with sequence similarity to prokaryotic enzymes involved in the degradation of aromatic compoundsHuman autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagyMMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO)The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interactionIdentification and characterization of human and mouse ovastacin: a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fishComparative analysis of cancer genes in the human and chimpanzee genomes.POT1 loss-of-function variants predispose to familial melanomaA genomic analysis of rat proteases and protease inhibitorsExome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndromeBiochemical characterization and crystalization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homologHallmarks of progeroid syndromes: lessons from mice and reprogrammed cellsNF-kB in premature agingA Novel Family of Soluble Minimal Scaffolds Provides Structural Insight into the Catalytic Domains of Integral Membrane MetallopeptidasesThe helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domainNuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancerClinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features
P50
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P50
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Spaans biochemicus
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عالم كيمياء حيوية إسباني
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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Carlos López Otín
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