Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases - Test2 - elhamkhani - TriplyDB

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

http://www.wikidata.org/entity/Q29247921

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Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?Neuroprotective Effects of Protein Tyrosine Phosphatase 1B Inhibition against ER Stress-Induced Toxicity.Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate.Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.ROS Modulator Molecules with Therapeutic Potential in Cancers Treatments.Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease.The Role of Free Radicals in Autophagy Regulation: Implications for Ageing.TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy

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Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

http://www.wikidata.org/entity/Q29247921

description

2017 nî lūn-bûn

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2017 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2017 թվականի ապրիլին հրատարակված գիտական հոդված

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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Modulation of proteostasis by ...... in neurodegenerative diseases

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Modulation of proteostasis by ...... in neurodegenerative diseases

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Modulation of proteostasis by ...... in neurodegenerative diseases

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Modulation of proteostasis by ...... in neurodegenerative diseases

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Antonio Cuadrado

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Marta Pajares

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

P2860

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

Role of Nrf2 in oxidative stress and toxicity

Redox regulation by Nrf2: gatekeeping for the basal and diabetes-induced expression of thioredoxin interacting protein

Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

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neurodegeneration

DNA-binding protein

transcription factor

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5239825

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