Silencers regulate both constitutive and alternative splicing events in mammals
about
Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domainsSplicing regulation: from a parts list of regulatory elements to an integrated splicing codeIdentification of an exonic splicing silencer in exon 6A of the human VEGF gene.Deletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing.Comparative component analysis of exons with different splicing frequenciesFunctional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.Repair of pre-mRNA splicing: prospects for a therapy for spinal muscular atrophy.Mechanistic control of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) splice isoforms by the heterogeneous nuclear ribonuclear proteins hnRNP L, hnRNP A1, and hnRNP M.'Genome design' model and multicellular complexity: golden middleStatistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regions.Mutually exclusive splicing regulates the Nav 1.6 sodium channel function through a combinatorial mechanism that involves three distinct splicing regulatory elements and their ligandsInvestigation of dmyc Promoter and Regulatory RegionsA computational approach for genome-wide mapping of splicing factor binding sites.Binding of DAZAP1 and hnRNPA1/A2 to an exonic splicing silencer in a natural BRCA1 exon 18 mutant.Frequent gain and loss of intronic splicing regulatory elements during the evolution of vertebrates.Identification of motifs that function in the splicing of non-canonical introns.Splicing of designer exons reveals unexpected complexity in pre-mRNA splicingPhylogenetically widespread alternative splicing at unusual GYNGYN donorsSplicing defects caused by exonic mutations in PKD1 as a new mechanism of pathogenesis in autosomal dominant polycystic kidney disease.Identification of RNA-binding proteins that regulate FGFR2 splicing through the use of sensitive and specific dual color fluorescence minigene assays.A comprehensive computational characterization of conserved mammalian intronic sequences reveals conserved motifs associated with constitutive and alternative splicing.Exon skipping through the creation of a putative exonic splicing silencer as a consequence of the cystic fibrosis mutation R553X.An exon skipping-associated nonsense mutation in the dystrophin gene uncovers a complex interplay between multiple antagonistic splicing elements.Tau exon 6 is regulated by an intricate interplay of trans factors and cis elements, including multiple branch points.A clinical, genetic, and biochemical characterization ofSPG7mutations in a large cohort of patients with hereditary spastic paraplegia
P2860
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P2860
Silencers regulate both constitutive and alternative splicing events in mammals
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Silencers regulate both constitutive and alternative splicing events in mammals
@ast
Silencers regulate both constitutive and alternative splicing events in mammals
@en
type
label
Silencers regulate both constitutive and alternative splicing events in mammals
@ast
Silencers regulate both constitutive and alternative splicing events in mammals
@en
prefLabel
Silencers regulate both constitutive and alternative splicing events in mammals
@ast
Silencers regulate both constitutive and alternative splicing events in mammals
@en
P1476
Silencers regulate both constitutive and alternative splicing events in mammals
@en
P2093
P2888
P304
P356
10.1007/S00018-005-5030-6
P577
2005-07-01T00:00:00Z
P6179
1007472604