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PTEN function: how normal cells control it and tumour cells lose itProtean PTEN: form and functionThe associations between Parkinson's disease and cancer: the plot thickensPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsPTEN plasticity: how the taming of a lethal gene can go too farThe potential origin of glioblastoma initiating cellsSubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersHyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in miceTargeting mutants of PTEN reveal distinct subsets of tumour suppressor functionsNO signaling and S-nitrosylation regulate PTEN inhibition in neurodegenerationPTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppressionNuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifsAn essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cellsInhibition of neuronal phenotype by PTEN in PC12 cellsThe adaptive significance of adult neurogenesis: an integrative approachActivation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons.Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.Modulation in activation and expression of phosphatase and tensin homolog on chromosome ten, Akt1, and 3-phosphoinositide-dependent kinase 1: further evidence demonstrating altered phosphoinositide 3-kinase signaling in postmortem brain of suicide sDifferent conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neuronsAAVshRNA-mediated suppression of PTEN in adult rats in combination with salmon fibrin administration enables regenerative growth of corticospinal axons and enhances recovery of voluntary motor function after cervical spinal cord injuryProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neuronsConditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development.AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressorDeregulated proliferation and differentiation in brain tumors.PTEN: Multiple Functions in Human Malignant TumorsMiR-486 regulates lactation and targets the PTEN gene in cow mammary glands.A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development.Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cellsFrequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.Differential roles of GluN2A- and GluN2B-containing NMDA receptors in neuronal survival and death.Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY.Active zone density is conserved during synaptic growth but impaired in aged mice.Phosphoinositide 5- and 3-phosphatase activities of a voltage-sensing phosphatase in living cells show identical voltage dependenceModulation of inositol polyphosphate levels regulates neuronal differentiationPten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex.Estrogen partially down-regulates PTEN to prevent apoptosis in VSC4.1 motoneurons following exposure to IFN-gamma.Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development.PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons.Brain patterning perturbations following PTEN loss.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A role for nuclear PTEN in neuronal differentiation.
@ast
A role for nuclear PTEN in neuronal differentiation.
@en
type
label
A role for nuclear PTEN in neuronal differentiation.
@ast
A role for nuclear PTEN in neuronal differentiation.
@en
prefLabel
A role for nuclear PTEN in neuronal differentiation.
@ast
A role for nuclear PTEN in neuronal differentiation.
@en
P2093
P3181
P1476
A role for nuclear PTEN in neuronal differentiation
@en
P2093
C M Schonhoff
M B Lachyankar
N S Litofsky
P J Quesenberry
P304
P3181
P356
10.1523/JNEUROSCI.20-04-01404.2000
P407
P577
2000-02-01T00:00:00Z