The genetic architecture of type 2 diabetes - Test2 - elhamkhani - TriplyDB

The genetic architecture of type 2 diabetes

The genetic architecture of type 2 diabetes

http://www.wikidata.org/entity/Q29583824

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Arsenic Exposure and Type 2 Diabetes: MicroRNAs as Mechanistic Links?Rare and low-frequency coding variants alter human adult height Human genetics as a model for target validation: finding new therapies for diabetes.Gene-Diet Interaction and Precision Nutrition in Obesity How Can Genetic Studies Help Us to Understand Links Between Birth Weight and Type 2 Diabetes?Exposing the exposures responsible for type 2 diabetes and obesity.Dissecting the genetics of complex traits using summary association statistics Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.Omics-squared: human genomic, transcriptomic and phenotypic data for genetic analysis workshop 19.Precision diabetes: learning from monogenic diabetes.The impact of rare and low-frequency genetic variants in common disease Prediction of gene expression with cis-SNPs using mixed models and regularization methods Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both?Introduction of the DiaGene study: clinical characteristics, pathophysiology and determinants of vascular complications of type 2 diabetes.Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons.Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells.Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes.Opportunities and challenges of whole-genome and -exome sequencing.LASER server: ancestry tracing with genotypes or sequence reads.Whole genome sequence analysis of serum amino acid levels.Assessment of Human Tribbles Homolog 3 Genetic Variation (rs2295490) Effects on Type 2 Diabetes Patients with Glucose Control and Blood Pressure Lowering Treatment.PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.Shortcuts to a functional adipose tissue: The role of small non-coding RNAs.Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction T2DiACoD: A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders.Concepts, estimation and interpretation of SNP-based heritability.Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities.CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study.Mechanisms of Type 2 Diabetes Risk Loci.Prioritising Causal Genes at Type 2 Diabetes Risk Loci.Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus.The role of human host genetics in tuberculosis resistance.Identifying and mitigating batch effects in whole genome sequencing data.Using Personalized Medicine in the Management of Diabetes Mellitus.Findings of a 1303 Korean whole-exome sequencing study.10 Years of GWAS Discovery: Biology, Function, and Translation.Improving power for rare-variant tests by integrating external controls.An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns.Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer.

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The genetic architecture of type 2 diabetes

http://www.wikidata.org/entity/Q29583824

description

2016 nî lūn-bûn

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2016 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2016 թվականի հուլիսին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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The genetic architecture of type 2 diabetes

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Aaron G. Day-Williams

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Alex S. F. Doney

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Alisa Manning

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Amy Swift

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Anders H. Rosengren

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Andrew D. Morris

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Andrew J. Farmer

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Andrew P. Morris

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Andrew R. Wood

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Anna L. Gloyn

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Sensitive detection of chromosomal segments of distinct ancestry in admixed populations

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

An integrated encyclopedia of DNA elements in the human genome

An integrated map of genetic variation from 1,092 human genomes

Finding the missing heritability of complex diseases

A Bayesian measure of the probability of false discovery in genetic epidemiology studies

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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4596160

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10.1038/NATURE18642

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7614

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536

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Gonçalo Abecasis

Andrew Tym Hattersley

Eleftheria Zeggini

Thomas Meitinger

Christian Gieger

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2016-07-11T00:00:00Z

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1036558635

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27398621

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type-2 diabetes

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5034897

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