about
Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43The H19 non-coding RNA is essential for human tumor growthBoundary cap cells constrain spinal motor neuron somal migration at motor exit points by a semaphorin-plexin mechanism.Designing of highly effective complementary and mismatch siRNAs for silencing a geneHuman MicroRNA targetsThe human mineral dust-induced gene, mdig, is a cell growth regulating gene associated with lung cancerNucleolin links to arsenic-induced stabilization of GADD5alpha mRNAA high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradationSupervillin modulation of focal adhesions involving TRIP6/ZRP-1The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherinZinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repairReciprocal regulation of extracellular signal regulated kinase 1/2 and mitogen activated protein kinase phosphatase-3Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersIdentification of the non-lysosomal glucosylceramidase as beta-glucosidase 2Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neuronsA computational study of off-target effects of RNA interferencedsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.The contributions of dsRNA structure to Dicer specificity and efficiency.The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphologyPolycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155.The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiationSfold web server for statistical folding and rational design of nucleic acidsCRE recombinase-inducible RNA interference mediated by lentiviral vectorsSmall RNA and transcriptional upregulationRNAi and RNAa--the yin and yang of RNAomeAP-2gamma promotes proliferation in breast tumour cells by direct repression of the CDKN1A geneH-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signalingSmall dsRNAs induce transcriptional activation in human cellsStress granules and processing bodies are dynamically linked sites of mRNP remodelingsiVirus: web-based antiviral siRNA design software for highly divergent viral sequencessiRNA target site secondary structure predictions using local stable substructuresSuppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels.Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionalityHuSiDa--the human siRNA database: an open-access database for published functional siRNA sequences and technical details of efficient transfer into recipient cellssiRNAdb: a database of siRNA sequencesE-RNAi: a web application to design optimized RNAi constructs.Tolerated wobble mutations in siRNAs decrease specificity, but can enhance activity in vivo.Single small-interfering RNA expression vector for silencing multiple transforming growth factor-beta pathway componentsFunctional polarity is introduced by Dicer processing of short substrate RNAs.Genome-wide selection of unique and valid oligonucleotides.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Rational siRNA design for RNA interference
@ast
Rational siRNA design for RNA interference
@en
type
label
Rational siRNA design for RNA interference
@ast
Rational siRNA design for RNA interference
@en
prefLabel
Rational siRNA design for RNA interference
@ast
Rational siRNA design for RNA interference
@en
P2093
P3181
P356
P1433
P1476
Rational siRNA design for RNA interference
@en
P2093
P2888
P304
P3181
P356
10.1038/NBT936
P407
P577
2004-03-01T00:00:00Z
P5875
P6179
1039709400