Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
about
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG islandThe p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancersHistone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2.The Ski protein family is required for MeCP2-mediated transcriptional repressionInvolvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencingMCAF mediates MBD1-dependent transcriptional repressionJagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2Location-specific epigenetic regulation of the metallothionein 3 gene in esophageal adenocarcinomas.SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activitiesWNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancerHistone deacetylases (HDACs): characterization of the classical HDAC familyThe MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomesA decade of exploring the cancer epigenome - biological and translational implicationsAn update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromesAn overview of epigenetics and chemopreventionHistone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agentsDNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancersA phase 2 study of vorinostat in acute myeloid leukemiaCpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 bindingGATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancerEpigenetics as a mechanism driving polygenic clinical drug resistancePromoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancerMethylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesisEpigenetic inactivation of CHFR in human tumorsRegulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegationSynergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivationThe netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitmentBreast cancer chemoprevention: beyond tamoxifenThe histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responsesBlockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis.Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sitesHistone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I studyEpigenetics of cervical cancer. An overview and therapeutic perspectivesAntineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines.Accurate quantification of DNA methylation using combined bisulfite restriction analysis coupled with the Agilent 2100 Bioanalyzer platform.A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancersEpigenetics in non-small cell lung cancer: from basics to therapeuticsGlobal histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment?
P2860
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P2860
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Synergy of demethylation and h ...... on of genes silenced in cancer
@ast
Synergy of demethylation and h ...... on of genes silenced in cancer
@en
type
label
Synergy of demethylation and h ...... on of genes silenced in cancer
@ast
Synergy of demethylation and h ...... on of genes silenced in cancer
@en
prefLabel
Synergy of demethylation and h ...... on of genes silenced in cancer
@ast
Synergy of demethylation and h ...... on of genes silenced in cancer
@en
P2093
P3181
P356
P1433
P1476
Synergy of demethylation and h ...... on of genes silenced in cancer
@en
P2093
P2888
P3181
P356
10.1038/5047
P407
P50
P577
1999-01-01T00:00:00Z
P6179
1020518662