Sirtuins in mammals: insights into their biological function - Test2 - elhamkhani - TriplyDB

Sirtuins in mammals: insights into their biological function

Sirtuins in mammals: insights into their biological function

http://www.wikidata.org/entity/Q29615248

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Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription JNK1 phosphorylates SIRT1 and promotes its enzymatic activity Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy SIRT1 deacetylates APE1 and regulates cellular base excision repair Synthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitors SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells Evolution of the arginase fold and functional diversity SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70 Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition Epigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral Deficits Role of Sirtuins in Linking Metabolic Syndrome with Depression Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders Sirtuins Link Inflammation and Metabolism Genetic and epigenetic aspects of initiation and progression of hepatocellular carcinoma Acylation of Biomolecules in Prokaryotes: a Widespread Strategy for the Control of Biological Function and Metabolic Stress Mitochondrial fatty acid oxidation in obesity Protective effects and mechanisms of sirtuins in the nervous system Sirtuin 1 and sirtuin 3: physiological modulators of metabolism SIRT1 as a therapeutic target in inflammaging of the pulmonary disease Growing the growth cone: remodeling the cytoskeleton to promote axon regeneration Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?SIRT1 and SIRT2: emerging targets in neurodegeneration NAD+ as a signaling molecule modulating metabolism Role of oligomeric proanthocyanidins derived from an extract of persimmon fruits in the oxidative stress-related aging process A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory Histone deacetylases and their role in motor neuron degeneration Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging T cell replicative senescence in human aging Redox regulation of SIRT1 in inflammation and cellular senescence HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38 The Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)

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Sirtuins in mammals: insights into their biological function

http://www.wikidata.org/entity/Q29615248

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Sirtuins in mammals: insights into their biological function

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Sirtuins in mammals: insights into their biological function

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Sirtuins in mammals: insights into their biological function

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Sirtuins in mammals: insights into their biological function

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Biochemical Journal

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Sirtuins in mammals: insights into their biological function

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Michan S

http://www.w3.org/2001/XMLSchema#string

Sinclair D

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P2860

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

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1-13

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scholarly article

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930893

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10.1042/BJ20070140

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1

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404

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17447894

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2753453

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