The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
about
Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistabilityBax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaOrdering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerSAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agentsPresence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cellsThe CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosisTID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functionsRegulation of acidification and apoptosis by SHP-1 and Bcl-2Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell deathThe HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition poreNitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosisModulation of mitochondrial gene expression in pulmonary epithelial cells exposed to oxidantsOxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosisActivation of K+ channels induces apoptosis in vascular smooth muscle cellsIdentification and characterization of GRIM-1, a cell-death-associated gene productActive Bax and Bak are functional holinsDaxx silencing sensitizes cells to multiple apoptotic pathwaysRegulation of cytochrome c oxidase activity by c-Src in osteoclastsIBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationGlutathione peroxidase-1 protects from CD95-induced apoptosisThe E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosisFas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivop28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulumInvolvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell deathThe c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspasesIAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspasesHuman IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome cApoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2Hsp27 as a negative regulator of cytochrome C release.NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosisRoles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosisForever young: mechanisms of natural anoxia tolerance and potential links to longevityThe pathogenic activation of calpain: a marker and mediator of cellular toxicity and disease statesDIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb developmentBcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activationCaspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosisalpha-Toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signalingCaspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosisSuppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteinsMitochondrial release of caspase-2 and -9 during the apoptotic process
P2860
Q21563509-68C6CAB7-9D12-4D22-9B5D-1CE6506ECA4DQ22008484-DF302024-8398-4453-B7A0-D24937077164Q22008727-5E8ACBDA-2A9B-4495-B315-3225502ED10CQ22009063-355D8F07-54B8-40C3-A3F0-205E1CC56848Q22009395-38327A76-6AB3-42F1-AD32-B1039F019106Q22009525-ACC6D4D4-7318-435B-97D3-4D3F07F7CD29Q22010402-45AE40C9-D2DE-4934-8C2F-84B261F9813BQ22010599-E93157CE-D84E-48CD-A847-68C0941D6DF5Q22010927-F1EBFF39-375C-40F7-822C-FE607E602989Q22011015-E51E121E-1597-426E-949B-CF1714296A87Q22254259-6813E4B1-25E5-49D0-B716-884103669B4EQ23923126-A7F9D353-9A91-4EE3-BA5F-B0C90B0E5BEAQ23923183-31B85212-1236-40EA-86E3-C6BAD7F2F408Q24290915-A01FA710-EED4-4E99-8541-B6639EB07B15Q24293246-A67C2938-74A1-4CBE-8E92-991C9A7AAD1FQ24293539-A969F95B-DA34-4C4B-B34B-778D0ACC416FQ24296344-C8303C84-5FDB-4C4A-95F1-541255DA40FBQ24296720-D717A335-AA12-403E-B20A-371FBEBB3C62Q24303971-E43D663C-01B3-4FE7-94A8-889E9D4088B1Q24306458-EC4EE9E3-AB40-41B1-A7B5-BC36A6C2759AQ24312877-EDBA785C-4E94-44C7-B725-A1F0B2B3B1BCQ24315092-D23DAF0C-A199-49CD-B686-B66357B29CA9Q24318875-3E3850E3-55A8-4468-8895-479D468C33B8Q24338605-08E9B865-B982-41D1-9CF1-582AF5889B38Q24532851-5CEB752E-7E75-43B1-B76F-9951CBBA1B5DQ24533214-D4137326-5C96-44CA-A5F2-F38F333C4C20Q24533921-E1F8CB8C-1AA5-4224-83A6-86F3F1E56946Q24534641-5AEB0F6A-66BC-4023-9A36-DF168A6775CAQ24536983-91F6F8D1-D1CF-4129-A099-5ADFFECCCB27Q24554454-724801FE-B709-409F-BD2D-5C901A7584DDQ24562044-8CFD5F06-A978-446A-AE53-A5900E7E4DEDQ24633593-0F235F0A-BAC0-4380-993C-C49E2D1080C8Q24643397-92A9D4CA-F025-4049-89E5-CDA7D2914847Q24644473-9981DA19-6C99-4028-9D65-5E1B8C4FE0E8Q24644892-BFDE8B9C-47A6-4248-A473-E8006EDA6189Q24647389-6805EAB2-1507-44C4-AE30-03E47241F279Q24653351-0CBCD4F1-A2BE-4A8D-B361-7013619719BFQ24669697-C52BAE66-95BC-4CB7-AC23-A21CF3106F81Q24673877-6A24D7F5-03F3-48BF-812B-493D2BE75F0EQ24676806-1A218B0F-EA5A-4F86-AD75-3F6E7EFAFB44
P2860
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@ast
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@en
type
label
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@ast
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@en
prefLabel
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@ast
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@en
P2093
P3181
P1433
P1476
The release of cytochrome c fr ...... Bcl-2 regulation of apoptosis
@en
P2093
Bossy-Wetzel E
Newmeyer DD
P304
P3181
P356
10.1126/SCIENCE.275.5303.1132
P407
P577
1997-02-21T00:00:00Z