HSP90 at the hub of protein homeostasis: emerging mechanistic insights
about
Heterozygous yeast deletion collection screens reveal essential targets of Hsp90An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machineLarge extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutationsHeat shock proteins as danger signals for cancer detectionLabel-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cellsQuantitative analysis of HSP90-client interactions reveals principles of substrate recognitionGlucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cyclesA quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathwaysHsp90-Tau complex reveals molecular basis for specificity in chaperone actionScaffold proteins: hubs for controlling the flow of cellular informationModel systems of protein-misfolding diseases reveal chaperone modifiers of proteotoxicityMechanisms of Hsp90 regulationBacterial Heat Shock Protein ActivityReview: The HSP90 molecular chaperone-an enigmatic ATPaseTargeting Cell Survival Proteins for Cancer Cell DeathRole of Heat-Shock Proteins in Cellular Function and in the Biology of FungiALK inhibitors in non-small cell lung cancer: the latest evidence and developmentsHsp90 Inhibitors for the Treatment of Chronic Myeloid LeukemiaHsp90: A New Player in DNA Repair?Adipogenesis is under surveillance of Hsp90 and the high molecular weight Immunophilin FKBP51Molecular mechanisms of robustness in plantsExpanding proteostasis by membrane trafficking networksDangER: protein ovERload. Targeting protein degradation to treat myelomaMacromolecule-assisted de novo protein foldingQuality control and fate determination of Hsp90 client proteinsMyosin chaperonesHeat shock proteins at the crossroads between cancer and Alzheimer's diseaseChemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosisTargeting the androgen receptor in prostate and breast cancer: several new agents in developmentKeep your heart in shape: molecular chaperone networks for treating heart diseaseChaperone machines for protein folding, unfolding and disaggregationHSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivoCorresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulationsThe molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouseThe architecture of functional modules in the Hsp90 co-chaperone Sti1/HopNMR structure and MD simulations of the AAA protease intermembrane space domain indicates peripheral membrane localization within the hexaoligomerContribution of chaperones to STAT pathway signaling.Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinaseMixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle.
P2860
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P2860
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@ast
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@en
type
label
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@ast
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@en
prefLabel
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@ast
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@en
P3181
P356
P1476
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
@en
P2093
Susan Lindquist
P2888
P304
P3181
P356
10.1038/NRM2918
P407
P577
2010-06-09T00:00:00Z
P5875
P6179
1019520858