A "silent" polymorphism in the MDR1 gene changes substrate specificity
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Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsidAssociation between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgeryDifferentiating protein-coding and noncoding RNA: challenges and ambiguitiesGenetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathyVariation in WNT genes is associated with non-syndromic cleft lip with or without cleft palateCodon usage: nature's roadmap to expression and folding of proteinsEvolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenariansSynonymous codon usage influences the local protein structure observedGenetic predictors of interindividual variability in hepatic CYP3A4 expressionDisruption of neurexin 1 associated with autism spectrum disorder.Identification of association of common AGGF1 variants with susceptibility for Klippel-Trenaunay syndrome using the structure association programExpanding the concepts in protein structure-function relationships and enzyme kinetics: Teaching using morpheeinsCommon MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopiaFrequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neckStrong purifying selection at synonymous sites in D. melanogasterThe effect of ABCB1 polymorphisms on the outcome of breast cancer treatmentThe dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutationsSilent Polymorphisms: Can the tRNA Population Explain Changes in Protein Properties?Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Decoding mechanisms by which silent codon changes influence protein biogenesis and functionRedundancy of the genetic code enables translational pausingMacromolecule-assisted de novo protein foldingPharmacogenetics and outcome with antipsychotic drugsMultiple roles of the coding sequence 5' end in gene expression regulationThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyRibonucleoprotein complexes that control circadian clocksAssociation of TLR7 variants with AIDS-like disease and AIDS vaccine efficacy in rhesus macaquesA Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-CellsSingle Synonymous Mutations in KRAS Cause Transformed Phenotypes in NIH3T3 CellsPharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineATP-binding cassette B1 gene polymorphisms, mRNA expression and chemosensitivity to paclitaxel in non-small cell lung cancer cells.Polymorphisms of the vincristine pathway and response to treatment in children with childhood acute lymphoblastic leukemiaThe DISC locus in psychiatric illnessDetecting positive and purifying selection at synonymous sites in yeast and wormInfluence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patientsDirected evolution of a G protein-coupled receptor for expression, stability, and binding selectivityLong-distance, graft-transmissible action of Arabidopsis FLOWERING LOCUS T protein to promote floweringGeographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversityPain genes
P2860
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P2860
A "silent" polymorphism in the MDR1 gene changes substrate specificity
description
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2007
@ast
im Januar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 26 January 2007)
@en
wetenschappelijk artikel (gepubliceerd op 2007/01/26)
@nl
наукова стаття, опублікована в січні 2007
@uk
مقالة علمية (نشرت في 26-1-2007)
@ar
name
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@ast
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@en
type
label
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@ast
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@en
prefLabel
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@ast
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@en
P2093
P50
P3181
P356
P1433
P1476
A "silent" polymorphism in the MDR1 gene changes substrate specificity
@en
P2093
In-Wha Kim
Michael M Gottesman
Suresh V Ambudkar
Zuben E Sauna
P304
P3181
P356
10.1126/SCIENCE.1135308
P407
P577
2006-12-21T00:00:00Z