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Irinotecan Pathway
Irinotecan Pathway
Item
http://www.wikidata.org/entity/Q29883346
Q29883346
about
Q29883366
sameAs
Irinotecan Pathway
Item
http://www.wikidata.org/entity/Q29883346
description
biological pathway in human
@en
name
Irinotecan Pathway
@en
type
Item
label
Irinotecan Pathway
@en
prefLabel
Irinotecan Pathway
@en
P2410
Q29883346-AC61F9C9-F59C-4FA5-8B2E-60245AD15E7A
P2860
Q29883346-41B674E5-626E-4EFA-9CA3-E5183A2D5825
Q29883346-830DB77A-9764-47EA-96B6-EB8CB0EAFE80
Q29883346-98F2E7A0-2BAE-4D25-916A-0E0C1FF85FC5
Q29883346-9B966965-178C-435B-8812-A3814C47E237
Q29883346-DAEA6491-3CA6-48DE-AFA1-85544F19BF52
Q29883346-EFFAFBFA-7D58-485F-BF4A-BA2DDF664E2A
P2888
Q29883346-624E1E5F-7659-4FC6-ACEC-2048A3956855
P31
Q29883346-3C15CE20-FCB3-4E02-A87F-9E864BE0560E
P527
Q29883346-110B4136-3985-4ECC-983A-98906E303C6C
Q29883346-2EB4B51A-AA77-453F-B059-049438887B47
Q29883346-3CD43CFC-F655-460D-90E0-32CBB0F72026
Q29883346-49C1D032-AC6E-47DA-B87D-1B90C3C38F5B
Q29883346-4AE719C8-1B9F-45A1-8FB8-64C59687EA4F
Q29883346-506887E6-5569-4EFE-A014-D3FF0E099297
Q29883346-618141A6-B6D0-4078-BA13-7F4CCE5BB906
Q29883346-6CC16C16-EFBA-43CB-931F-FAF6D1F0F212
Q29883346-87FA5EAD-4CE0-4C67-ACB4-F05694515401
Q29883346-88D7FDA4-318A-4064-8561-5B7E8B2F89B1
Show more
P703
Q29883346-7853A478-8BF7-494F-BDF2-BD727FC67A87
P2410
WP229
http://www.w3.org/2001/XMLSchema#string
P2860
The anticancer prodrug CPT-11 is a potent inhibitor of acetylcholinesterase but is rapidly catalyzed to SN-38 by butyrylcholinesterase
ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P
Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans
A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4
Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin
Irinotecan pathway genotype analysis to predict pharmacokinetics
P2888
WP229
P31
biological pathway
P527
CYP3A4
UGT1A1
BCHE
NPC1
7-ethyl-10-hydroxycamptothecin
ABCC2
CYP3A5
ABCC1
CES2
SLCO1B1
Show more
P703
Homo sapiens