T-cell quality in memory and protection: implications for vaccine design - Test2 - elhamkhani - TriplyDB

T-cell quality in memory and protection: implications for vaccine design

T-cell quality in memory and protection: implications for vaccine design

http://www.wikidata.org/entity/Q30014840

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Evaluation of the sublingual route for administration of influenza H5N1 virosomes in combination with the bacterial second messenger c-di-GMP Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin Vaccines for gonorrhea: can we rise to the challenge?A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis Microchip platforms for multiplex single-cell functional proteomics with applications to immunology and cancer research In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells Emerging concepts in the immunopathogenesis of AIDS Human T cell responses to Japanese encephalitis virus in health and disease Differential expression of CD300a/c on human TH1 and TH17 cells Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines mTOR regulates memory CD8 T-cell differentiation Immunotherapy for tuberculosis: future prospects The Role of Lymphatic Niches in T Cell Differentiation Cutaneous Leishmaniasis Vaccination: A Matter of Quality Balancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza Infection Novel technologies and emerging biomarkers for personalized cancer immunotherapy Development and Function of Protective and Pathologic Memory CD4 T Cells Measuring Cellular Immunity to Influenza: Methods of Detection, Applications and Challenges Tregs in infection and vaccinology: heroes or traitors?Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis CD4 T-cell subsets in malaria: TH1/TH2 revisited Systems biology in vaccine design Human memory T cells: generation, compartmentalization and homeostasis Effective T helper cell responses against retroviruses: are all clonotypes equal?Immune response to mycobacterial infection: lessons from flow cytometry Chimeric antigen receptor therapy for cancer Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment Fusion of the Mycobacterium tuberculosis antigen 85A to an oligomerization domain enhances its immunogenicity in both mice and non-human primates Comparing adjuvanted H28 and modified vaccinia virus ankara expressingH28 in a mouse and a non-human primate tuberculosis model A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent models Characterization of anamnestic T-cell responses induced by conventional vaccines against contagious bovine pleuropneumonia Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo Testing the H56 Vaccine Delivered in 4 Different Adjuvants as a BCG-Booster in a Non-Human Primate Model of Tuberculosis T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting Modulation of Trypanosoma cruzi-specific T-cell responses after chemotherapy for chronic Chagas disease Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis Adaptive immunity against Leishmania nucleoside hydrolase maps its c-terminal domain as the target of the CD4+ T cell-driven protective response

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T-cell quality in memory and protection: implications for vaccine design

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Nature Reviews Immunology

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T-cell quality in memory and protection: implications for vaccine design

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Darrah PA

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Roederer M

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Seder RA

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P2860

Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load.

Experimental approaches to mechanisms of protection and pathogenesis in M. tuberculosis infection.

Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes.

Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity.

Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors.

Cutting edge: effector memory CD8+ T cells play a prominent role in recall responses to secondary viral infection in the lung.

Immune elimination of Leishmania major in mice: implications for immune memory, vaccination, and reactivation disease.

Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.

Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L.

High numbers of IL-2-producing CD8+ T cells during viral infection: correlation with stable memory development.

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1310338

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10.1038/NRI2274

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5528190

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18323851

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