Spheroid-based drug screen: considerations and practical approach - Test2 - elhamkhani - TriplyDB

Spheroid-based drug screen: considerations and practical approach

Spheroid-based drug screen: considerations and practical approach

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Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug development 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids Microtissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D Microenvironment Cancer Stem Cells in the Thyroid In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform Mass spectrometry imaging of therapeutics from animal models to three-dimensional cell cultures Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy Microscale screening systems for 3D cellular microenvironments: platforms, advances, and challenges Scaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat Aortae Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion High-Throughput Single-Cell Derived Sphere Formation for Cancer Stem-Like Cell Identification and Analysis.Microstamped Petri dishes for scanning electrochemical microscopy analysis of arrays of microtissues Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responses Multicellular tumor spheroids for evaluation of cytotoxicity and tumor growth inhibitory effects of nanomedicines in vitro: a comparison of docetaxel-loaded block copolymer micelles and Taxotere®Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells Multiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheres Modulation of Huh7.5 spheroid formation and functionality using modified PEG-based hydrogels of different stiffness Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B Multizone paper platform for 3D cell cultures High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.Engineering cancer microenvironments for in vitro 3-D tumor models.Optimization of Aqueous Biphasic Tumor Spheroid Microtechnology for Anti-Cancer Drug Testing in 3D Culture Human adipose stem cells maintain proliferative, synthetic and multipotential properties when suspension cultured as self-assembling spheroids.Polymeric nanoparticles enhance the sonodynamic activity of meso-tetrakis (4-sulfonatophenyl) porphyrin in an in vitro neuroblastoma model Microengineering methods for cell-based microarrays and high-throughput drug-screening applications Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation.In vitro optimization of EtNBS-PDT against hypoxic tumor environments with a tiered, high-content, 3D model optical screening platform.Novel Phenotypic Fluorescent Three-Dimensional Platforms for High-throughput Drug Screening and Personalized Chemotherapy.Live multicellular tumor spheroid models for high-content imaging and screening in cancer drug discovery.The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells.Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids.Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination.A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging.

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Spheroid-based drug screen: considerations and practical approach

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2009 nî lūn-bûn

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2009年の論文

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Spheroid-based drug screen: considerations and practical approach

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Spheroid-based drug screen: considerations and practical approach

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Claudia Seidel

http://www.w3.org/2001/XMLSchema#string

Juergen Friedrich

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Leoni A Kunz-Schughart

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Reinhard Ebner

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P2860

Hyperbolastic growth models: theory and application

Experimental approaches to kinetics of gas diffusion in hydrogenase

Identification and expansion of human colon-cancer-initiating cells

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

Identification of human brain tumour initiating cells

Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation

CD133: molecule of the moment

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

Drug penetration in solid tumours

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309-324

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834412

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10.1038/NPROT.2008.226

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3

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1013942825

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