Spheroid-based drug screen: considerations and practical approach
about
Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug development384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroidsMicrotissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D MicroenvironmentCancer Stem Cells in the ThyroidIn Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right PlatformMass spectrometry imaging of therapeutics from animal models to three-dimensional cell culturesOpportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacyMicroscale screening systems for 3D cellular microenvironments: platforms, advances, and challengesScaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat AortaeAssay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid CulturesTensile Forces Originating from Cancer Spheroids Facilitate Tumor InvasionHigh-Throughput Single-Cell Derived Sphere Formation for Cancer Stem-Like Cell Identification and Analysis.Microstamped Petri dishes for scanning electrochemical microscopy analysis of arrays of microtissuesInduced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous SystemControlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responsesMulticellular tumor spheroids for evaluation of cytotoxicity and tumor growth inhibitory effects of nanomedicines in vitro: a comparison of docetaxel-loaded block copolymer micelles and Taxotere®Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance modelEstablishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cellsMultiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheresModulation of Huh7.5 spheroid formation and functionality using modified PEG-based hydrogels of different stiffnessGeneration of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug TestingCo-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor MicroenvironmentA 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatmentImmunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme BMultizone paper platform for 3D cell culturesHigh-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional modelsNOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.Engineering cancer microenvironments for in vitro 3-D tumor models.Optimization of Aqueous Biphasic Tumor Spheroid Microtechnology for Anti-Cancer Drug Testing in 3D CultureHuman adipose stem cells maintain proliferative, synthetic and multipotential properties when suspension cultured as self-assembling spheroids.Polymeric nanoparticles enhance the sonodynamic activity of meso-tetrakis (4-sulfonatophenyl) porphyrin in an in vitro neuroblastoma modelMicroengineering methods for cell-based microarrays and high-throughput drug-screening applicationsAdvances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation.In vitro optimization of EtNBS-PDT against hypoxic tumor environments with a tiered, high-content, 3D model optical screening platform.Novel Phenotypic Fluorescent Three-Dimensional Platforms for High-throughput Drug Screening and Personalized Chemotherapy.Live multicellular tumor spheroid models for high-content imaging and screening in cancer drug discovery.The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells.Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids.Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination.A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging.
P2860
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P2860
Spheroid-based drug screen: considerations and practical approach
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Spheroid-based drug screen: considerations and practical approach
@ast
Spheroid-based drug screen: considerations and practical approach
@en
type
label
Spheroid-based drug screen: considerations and practical approach
@ast
Spheroid-based drug screen: considerations and practical approach
@en
prefLabel
Spheroid-based drug screen: considerations and practical approach
@ast
Spheroid-based drug screen: considerations and practical approach
@en
P2093
P2860
P3181
P356
P1433
P1476
Spheroid-based drug screen: considerations and practical approach
@en
P2093
Claudia Seidel
Juergen Friedrich
Leoni A Kunz-Schughart
Reinhard Ebner
P2860
P2888
P304
P3181
P356
10.1038/NPROT.2008.226
P577
2009-02-01T00:00:00Z
P5875
P6179
1013942825