Identification of a collapsed intermediate with non-native long-range interactions on the folding pathway of a pair of Fyn SH3 domain mutants by NMR relaxation dispersion spectroscopy.
about
Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein foldingThe energetics of a three-state protein folding system probed by high-pressure relaxation dispersion NMR spectroscopy.Population shuffling between ground and high energy excited states.Intrinsic unfoldase/foldase activity of the chaperonin GroEL directly demonstrated using multinuclear relaxation-based NMR.Electrostatic effects in the folding of the SH3 domain of the c-Src tyrosine kinase: pH-dependence in 3D-domain swapping and amyloid formationInsights into the folding and unfolding processes of wild-type and mutated SH3 domain by molecular dynamics and replica exchange molecular dynamics simulations.A residue in helical conformation in the native state adopts a β-strand conformation in the folding transition state despite its high and canonical Φ-value.Mutational investigation of protein folding transition states by Phi-value analysis and beyond: lessons from SH3 domain folding.Relaxation dispersion NMR spectroscopy as a tool for detailed studies of protein folding.Phi-value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy.beta-Strand interactions at the domain interface critical for the stability of human lens gammaD-crystallinNonnative interactions in coupled folding and binding processes of intrinsically disordered proteins.The origin of nonmonotonic complex behavior and the effects of nonnative interactions on the diffusive properties of protein foldingCharacterization of a transient unfolding intermediate in a core mutant of γS-crystallin.Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways.Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similarObservation of sequential steps in the folding of intestinal fatty acid binding protein using a slow folding mutant and 19F NMR.Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling.The folding transition state of protein L is extensive with nonnative interactions (and not small and polarized).Protein folding and unfolding studied at atomic resolution by fast two-dimensional NMR spectroscopyNMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers.Kinetic barriers and the role of topology in protein and RNA foldingNMR spectroscopy brings invisible protein states into focus.What lessons can be learned from studying the folding of homologous proteins?The folding of single domain proteins--have we reached a consensus?Folding of apomyoglobin: Analysis of transient intermediate structure during refolding using quick hydrogen deuterium exchange and NMR.Phi-value analysis for ultrafast folding proteins by NMR relaxation dispersion.The effect of C-terminal helix on the stability of FF domain studied by molecular dynamics simulationEnergetic frustrations in protein folding at residue resolution: a homologous simulation study of Im9 proteins.Conformational exchange of aromatic side chains characterized by L-optimized TROSY-selected ¹³C CPMG relaxation dispersion.Quantifying the structural requirements of the folding transition state of protein A and other systems.A simple method for measuring signs of (1)H (N) chemical shift differences between ground and excited protein statesThe low populated folding intermediate of a mutant of the Fyn SH3 domain identified by a simple model.Nonnative Energetic Frustrations in Protein Folding at Residual Level: A Simulation Study of Homologous Immunoglobulin-like β-Sandwich Proteins.
P2860
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P2860
Identification of a collapsed intermediate with non-native long-range interactions on the folding pathway of a pair of Fyn SH3 domain mutants by NMR relaxation dispersion spectroscopy.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of a collapsed ...... ation dispersion spectroscopy.
@ast
Identification of a collapsed ...... ation dispersion spectroscopy.
@en
type
label
Identification of a collapsed ...... ation dispersion spectroscopy.
@ast
Identification of a collapsed ...... ation dispersion spectroscopy.
@en
prefLabel
Identification of a collapsed ...... ation dispersion spectroscopy.
@ast
Identification of a collapsed ...... ation dispersion spectroscopy.
@en
P2093
P50
P1476
Identification of a collapsed ...... ation dispersion spectroscopy.
@en
P2093
Alan R Davidson
D Ranjith Muhandiram
Wing-Yiu Choy
P304
P356
10.1016/J.JMB.2006.08.047
P407
P577
2006-08-22T00:00:00Z