Small-angle X-ray scattering reveals an extended organization for the autoinhibitory resting state of the p47(phox) modular protein.
about
Molecular insights of p47phox phosphorylation dynamics in the regulation of NADPH oxidase activation and superoxide production.Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation.NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action.p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex.Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activationA regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox.p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.Regulation of NADPH oxidase activity in phagocytes: relationship between FAD/NADPH binding and oxidase complex assembly.Structural Insight into the 14-3-3 Protein-dependent Inhibition of Protein Kinase ASK1 (Apoptosis Signal-regulating kinase 1).Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synucleinInvestigating alternative acidic proteases for H/D exchange coupled to mass spectrometry: plasmepsin 2 but not plasmepsin 4 is active under quenching conditions.Conformational changes in p47(phox) upon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis.Down-regulation of NOX2 activity in phagocytes mediated by ATM-kinase dependent phosphorylation.Exploring the arachidonic acid-induced structural changes in phagocyte NADPH oxidase p47(phox) and p67(phox) via thiol accessibility and SRCD spectroscopy.
P2860
Q30009389-CE8B26FC-5CAC-4161-9BB6-360F0A900840Q30009954-30C5731B-BA2A-45FC-BF28-38CBF72DA72AQ30155581-5B5237D5-4F4B-434A-BB35-658DB42D6862Q30156808-75E8DDEF-8112-4A83-A972-C168C0A7836CQ30157617-1C0E75E9-32CF-4872-9E6D-EECE8C1EABBEQ30478913-8C992A33-96A2-4FDF-8B13-B07B842FC353Q30497179-E5A27E8E-45B0-4D30-BB3C-52575AFB6986Q33569648-76E7CE7A-659F-46A2-A7A0-82535A006DC1Q34236767-F8476A46-1468-4DDA-973D-AFB1E5344844Q41161844-259FDACE-CADB-46CB-9E56-97E95DA5C5FBQ41845296-74FCF520-F746-44CC-825A-EE6AB139E7E1Q43244226-71112070-E8C1-4FE3-873C-BA320387E323Q46133960-084B62E0-0B43-47EC-AFF1-608ACC96C3E1Q50062562-A61C8C0A-4B9A-4FB7-A073-DD4244AC7463Q51710433-4E13A8C2-5C99-4582-87AC-05A64D566E00
P2860
Small-angle X-ray scattering reveals an extended organization for the autoinhibitory resting state of the p47(phox) modular protein.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@ast
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@en
type
label
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@ast
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@en
prefLabel
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@ast
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@en
P2093
P356
P1433
P1476
Small-angle X-ray scattering r ...... the p47(phox) modular protein.
@en
P2093
Dominique Cannella
Dominique Durand
Franck Fieschi
Patrice Vachette
Virginie Dubosclard
P304
P356
10.1021/BI060274K
P407
P577
2006-06-01T00:00:00Z