Imatinib and Chronic Myeloid Leukemia - Test2 - elhamkhani - TriplyDB

Imatinib and Chronic Myeloid Leukemia

Imatinib and Chronic Myeloid Leukemia

http://www.wikidata.org/entity/Q30230734

about

Imatinib and Chronic Myeloid Leukemia

http://www.wikidata.org/entity/Q30230734

description

Hematopoietic Stem Cells found ...... sed by the Philadelphia tra...

@en

name

Imatinib and Chronic Myeloid Leukemia

@en

type

label

Imatinib and Chronic Myeloid Leukemia

@en

prefLabel

Imatinib and Chronic Myeloid Leukemia

@en

P1050

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Q30230734-302D8706-A157-4E53-9F46-72317B8213F3

P1050

chronic myeloid leukemia

P1476

Imatinib and Chronic Myeloid Leukemia

@en

P2093

Alexander Pico

http://www.w3.org/2001/XMLSchema#string

Kristina Hanspers

http://www.w3.org/2001/XMLSchema#string

P2410

WP3640

http://www.w3.org/2001/XMLSchema#string

P2860

The PVT-1 oncogene is a Myc protein target that is overexpressed in transformed cells.

PVT1: a rising star among oncogenic long noncoding RNAs.

Strategies to overcome resistance to targeted protein kinase inhibitors.

MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).

Myc and PI3K/AKT signaling cooperatively repress FOXO3a-dependent PUMA and GADD45a gene expression.

BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells

P2888

P31

biological pathway

P50

Alexander R. Pico

P527

P703

P921

disease pathway