about
Genome of the avirulent human-infective trypanosome--Trypanosoma rangeliPredicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae familyThe bacterium endosymbiont of Crithidia deanei undergoes coordinated division with the host cell nucleusVisual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infectionCo-ordinated expression of lymphoid and myeloid specific transcription factors during B-1b cell differentiation into mononuclear phagocytes in vitroLytic activity and structural differences of amphipathic peptides derived from trialysin.Hydrolase and sialyltransferase activities of trypanosoma cruzi trans-sialidase towards NeuAc-alpha-2,3-gal-Gal-beta-O-PNP.Two distinct groups of mucin-like genes are differentially expressed in the developmental stages of Trypanosoma cruzi.Triapsin, an unusual activatable serine protease from the saliva of the hematophagous vector of Chagas' disease Triatoma infestans (Hemiptera: Reduviidae).Post-translational modifications of Trypanosoma cruzi histone H4.The Trypanosoma cruzi nucleic acid binding protein Tc38 presents changes in the intramitochondrial distribution during the cell cycleOral exposure to Phytomonas serpens attenuates thrombocytopenia and leukopenia during acute infection with Trypanosoma cruzi.'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase.Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside librariesThree-dimensional reconstruction of Trypanosoma cruzi epimastigotes and organelle distribution along the cell division cycle.Nuclear structure of Trypanosoma cruzi.Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease.Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms.The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles.Chromosome localization changes in the Trypanosoma cruzi nucleusDifferential expression profiles in the midgut of Triatoma infestans infected with Trypanosoma cruziIron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.Characterization of Trypanosoma cruzi Sirtuins as Possible Drug Targets for Chagas Disease.Specialising the parasite nucleus: Pores, lamins, chromatin, and diversity.Novel membrane-bound eIF2alpha kinase in the flagellar pocket of Trypanosoma bruceiCharacterization of the plasma glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD).Chromatin and nuclear organization in Trypanosoma cruzi.Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development.T rypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas' disease.Chromatin modifications in trypanosomes due to stress.Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei.Temperature differences for trans-glycosylation and hydrolysis reaction reveal an acceptor binding site in the catalytic mechanism of Trypanosoma cruzi trans-sialidase.Catalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi.Phosphorylation of eIF2α on Threonine 169 is not required for Trypanosoma brucei cell cycle arrest during differentiation.Effect of ionizing radiation exposure on Trypanosoma cruzi Ubiquitin-Proteasome System.Secreted trypanosome cyclophilin inactivates lytic insect defense peptides and induces parasite calcineurin activation and infectivityIdentification of the telomere in Trypanosoma cruzi reveals highly heterogeneous telomere lengths in different parasite strains.Differential effects of alpha-helical and beta-hairpin antimicrobial peptides against Acanthamoeba castellanii.Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment.
P50
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P50
description
hulumtues
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հետազոտող
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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Sergio Schenkman
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P1053
A-9227-2013
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0000-0001-9353-8480