Coevolutionary signals across protein lineages help capture multiple protein conformations.
about
Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamicsFrom residue coevolution to protein conformational ensembles and functional dynamics.Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and proteaseLarge-Scale Conformational Transitions and Dimerization Are Encoded in the Amino-Acid Sequences of Hsp70 ChaperonesConstructing sequence-dependent protein models using coevolutionary information.Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.Accurate contact predictions using covariation techniques and machine learning.Potts Hamiltonian models of protein co-variation, free energy landscapes, and evolutionary fitness.Robust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information.Inference of Epistatic Effects Leading to Entrenchment and Drug Resistance in HIV-1 Protease.Biophysics of protein evolution and evolutionary protein biophysicsTMFoldRec: a statistical potential-based transmembrane protein fold recognition tool.Capturing coevolutionary signals inrepeat proteins.Comparative sequence analysis suggests a conserved gating mechanism for TRP channels.Evolutionary Conserved Positions Define Protein Conformational DiversityThe Maximum Entropy Fallacy Redux?Dimeric interactions and complex formation using direct coevolutionary couplings.The Phylogenetic Signature Underlying ATP Synthase c-Ring Compliance.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationInteractions between mitoNEET and NAF-1 in cells.Inferring repeat-protein energetics from evolutionary information.Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy.Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins.The Gearbox of the Bacterial Flagellar Motor Switch.Connecting the Sequence-Space of Bacterial Signaling Proteins to Phenotypes Using Coevolutionary Landscapes.Elucidating the druggable interface of protein-protein interactions using fragment docking and coevolutionary analysis.Toward rationally redesigning bacterial two-component signaling systems using coevolutionary information.A theoretical view of protein dynamics.Protein structure prediction: making AWSEM AWSEM-ER by adding evolutionary restraints.Epistasis in protein evolution.Revealing protein networks and gene-drug connectivity in cancer from direct information.Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by direct coupling analysis.Coevolutionary constraints in the sequence-space of macromolecular complexes reflect their self-assembly pathways.Structural propensities of kinase family proteins from a Potts model of residue co-variation.BIS2Analyzer: a server for co-evolution analysis of conserved protein families.Co-evolution techniques are reshaping the way we do structural bioinformatics.Structured States of Disordered Proteins from Genomic SequencesEnhanced unbiased sampling of protein dynamics using evolutionary coupling information.The challenge of modeling protein assemblies: The CASP12-CAPRI experiment.Attractor Structures of Signaling Networks: Consequences of Different Conformational Barcode Dynamics and Their Relations to Network-Based Drug Design.
P2860
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P2860
Coevolutionary signals across protein lineages help capture multiple protein conformations.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Coevolutionary signals across ...... ultiple protein conformations.
@ast
Coevolutionary signals across ...... ultiple protein conformations.
@en
type
label
Coevolutionary signals across ...... ultiple protein conformations.
@ast
Coevolutionary signals across ...... ultiple protein conformations.
@en
prefLabel
Coevolutionary signals across ...... ultiple protein conformations.
@ast
Coevolutionary signals across ...... ultiple protein conformations.
@en
P2860
P356
P1476
Coevolutionary signals across ...... ultiple protein conformations.
@en
P2093
Biman Jana
Faruck Morcos
P2860
P304
20533-20538
P356
10.1073/PNAS.1315625110
P407
P577
2013-12-02T00:00:00Z