Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus.
about
Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complexNucleocytoplasmic shuttling of influenza A virus proteinsVirus strategies for passing the nuclear envelope barrierViral quasispecies evolutionNovel Polymerase Gene Mutations for Human Adaptation in Clinical Isolates of Avian H5N1 Influenza VirusesNucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin 5Structural and Functional Characterization of K339T Substitution Identified in the PB2 Subunit Cap-binding Pocket of Influenza A VirusAirborne transmission of highly pathogenic H7N1 influenza virus in ferretsAvian influenza A viruses: from zoonosis to pandemicHost adaptation and transmission of influenza A viruses in mammalsInfluenza: from zoonosis to pandemicAvian influenza A H5N1 virus: a continuous threat to humans.Influenza pathogenicity during pregnancy in women and animal models.Virus-specific factors associated with zoonotic and pandemic potential.PB2 mutations D701N and S714R promote adaptation of an influenza H5N1 virus to a mammalian hostMolecular determinants of influenza virus pathogenesis in mice.Interactome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication.Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells.Mammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus.Targeting Importin-α7 as a Therapeutic Approach against Pandemic Influenza Viruses.Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.PB2-Q591K Mutation Determines the Pathogenicity of Avian H9N2 Influenza Viruses for Mammalian SpeciesInhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy.Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011.H5N1 pathogenesis studies in mammalian models.Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrierAsparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza A virus.Emerging antiviral strategies to interfere with influenza virus entry.A putative pH-dependent nuclear localization signal in the juxtamembrane region of c-MetIdentification of importin α 7 specific transport cargoes using a proteomic screening approach.Importin-α7 is required for enhanced influenza A virus replication in the alveolar epithelium and severe lung damage in mice.A crucial role of N-terminal domain of influenza A virus M1 protein in interaction with swine importin α1 protein.Human-like PB2 627K influenza virus polymerase activity is regulated by importin-α1 and -α7.HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replicationCellular protein HAX1 interacts with the influenza A virus PA polymerase subunit and impedes its nuclear translocationImportin α3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport functionUV-induced nuclear import of XPA is mediated by importin-α4 in an ATR-dependent mannerElucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicityMolecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7.
P2860
Q21135288-C824AD5E-B615-45E2-9F90-AC5516748802Q26852688-CFCAC4C9-77A8-4E98-BE22-A794C6FD8F7AQ26866395-B7C0CDEF-F565-4A9C-B69D-B1CFE8F9C658Q27013917-05FFFF47-142E-4232-A25B-07AE6B44F2A4Q27314657-AC3F8AFB-C432-4099-A2CA-EC19B368EBF2Q27675889-700B32DF-4713-49A8-8F0A-ED7BB90F0DC0Q27676615-CD1E59A9-195C-40E5-BAAD-CAC5925FCD16Q28387714-8643556C-4600-4B00-9F95-901382D2C421Q28393914-731B4A14-4102-4D67-86A4-B985552E7205Q28397046-468F20A3-8992-435C-9AC3-BB933C8504C7Q28596741-22E4B729-4436-498C-A10B-9C85A368041FQ30224462-3F00002F-30B2-4790-840D-2A23D9CD4F29Q30249129-D9C4E5B3-5ED1-4811-8D2C-54F84737B75CQ30353598-1E8180D3-D262-4379-B149-3900A3FA2B07Q30363302-58F1A6A9-503B-431D-87C3-413D3D48CE9CQ30364868-ABFD7619-A601-489F-9EAE-D068523A98BEQ30366402-6C474377-BCDD-41BE-8CBD-4B9754E0CEDAQ30366669-7AF2E33B-D999-4C8C-B219-0BF23FEDA126Q30371198-7DEE82F5-8DE5-446E-B38B-66AAFA1A9D01Q30375788-6655D1D9-40E0-4D0A-A926-A00C86006695Q30385766-B40A6D0D-1B83-4DD6-A410-2811E785BDF9Q30393577-B73F8210-5B55-4889-BB64-A9E6AFFFFD9AQ30403013-1B5D219A-5D8D-4F8A-B1E6-BB433F1648CBQ30404203-CC1858DE-8CFB-428F-A8B0-55EFBD4B452AQ30417814-15C845F9-32ED-4F8C-86DE-6F1E8FDAF6D3Q30427806-E0ADA0A7-5923-4C43-BCB3-F6543DE1A0F5Q30429748-3F94A7E6-8392-4B74-B02B-959B66FC181DQ30432390-43015D1F-0B1B-4955-A4AB-4E346E6E49E1Q30432421-1B691020-44B2-40D8-B010-636A35A10E53Q30596960-E1EB5047-B054-4BD2-BC91-CD6FDDF37F95Q33583177-E48C92A7-06A9-4A0A-B2EA-5DFBAC4373E4Q33900268-2795C26B-23C4-4B11-BB23-3AB67FFFBB1FQ33954072-553DF3A4-4E96-4A05-84BA-40AD29767FE7Q34139960-AAA34BA6-4A29-497B-9FFF-F2981771C885Q34303782-DAA89018-86EA-4D9B-9D1C-1D851D2ED527Q34440497-B3B090A5-326E-4805-8A1C-D749CBDC1027Q34576946-8CE0D80E-6342-49AC-B26E-22E64D7026F1Q34827179-CEBC2916-FE5E-499F-9415-0A63A6E911B7Q34898131-F9441843-B7D3-4B4F-9B81-798BE502AB9BQ35136748-1891563C-8E81-4AA9-9E47-01D8C513CB5A
P2860
Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Differential use of importin-α ...... adaptation of influenza virus.
@ast
Differential use of importin-α ...... adaptation of influenza virus.
@en
type
label
Differential use of importin-α ...... adaptation of influenza virus.
@ast
Differential use of importin-α ...... adaptation of influenza virus.
@en
prefLabel
Differential use of importin-α ...... adaptation of influenza virus.
@ast
Differential use of importin-α ...... adaptation of influenza virus.
@en
P2093
P2860
P50
P356
P1476
Differential use of importin-α ...... adaptation of influenza virus.
@en
P2093
Ben Hudjetz
Björn Keiner
Enno Hartmann
Franziska Rother
George G Brownlee
Gökhan Arman-Kalcek
Karin Klingel
Sigrid Baumgarte
Swantje Thiele
P2860
P2888
P356
10.1038/NCOMMS1158
P407
P577
2011-01-01T00:00:00Z
P5875
P6179
1028829643