High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
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Synergy Maps: exploring compound combinations using network-based visualizationA High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell ModelsPfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockersLarge-scale pharmacological profiling of 3D tumor models of cancer cells.Novel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screeningInvestigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations.SynergyFinder: a web application for analyzing drug combination dose-response matrix data.Drug combination therapy increases successful drug repositioning.mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening.Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors.Real-time viability and apoptosis kinetic detection method of 3D multicellular tumor spheroids using the Celigo Image Cytometer.A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials.Phenotypic Screens in Antimalarial Drug Discovery.Collaborative drug discovery for More Medicines for Tuberculosis (MM4TB).Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation.Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities.Direct and indirect approaches to identify drug modes of action.Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria.Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells.A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivationUsing Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures
P2860
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P2860
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
High-throughput matrix screeni ...... antimalarial drug combinations
@ast
High-throughput matrix screeni ...... antimalarial drug combinations
@en
type
label
High-throughput matrix screeni ...... antimalarial drug combinations
@ast
High-throughput matrix screeni ...... antimalarial drug combinations
@en
prefLabel
High-throughput matrix screeni ...... antimalarial drug combinations
@ast
High-throughput matrix screeni ...... antimalarial drug combinations
@en
P2093
P2860
P50
P356
P1433
P1476
High-throughput matrix screeni ...... antimalarial drug combinations
@en
P2093
Adam R Renslo
Amila Siriwardana
Crystal McKnight
Dongbo Liu
Hongmao Sun
James Inglese
Katy S Sherlach
Lesley A Mathews-Griner
Marc Ferrer
P2860
P2888
P356
10.1038/SREP13891
P407
P577
2015-09-25T00:00:00Z
P5875
P6179
1007183678