Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice.
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Evaluation of the sublingual route for administration of influenza H5N1 virosomes in combination with the bacterial second messenger c-di-GMPCyclic di-GMP: the first 25 years of a universal bacterial second messengerRationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvantsFunctional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice techniqueIntranasal vaccination with a plant-derived H5 HA vaccine protects mice and ferrets against highly pathogenic avian influenza virus challenge.Induction of Local Secretory IgA and Multifunctional CD4⁺ T-helper Cells Following Intranasal Immunization with a H5N1 Whole Inactivated Influenza Virus Vaccine in BALB/c Mice.The human potential of a recombinant pandemic influenza vaccine produced in tobacco plants.A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine.The duration of antigen-stimulation significantly alters the diversity of multifunctional CD4 T cells measured by intracellular cytokine stainingIntranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2', 3'-cGAMP VacciGrade™ adjuvant exacerbates viremia after virus challenge.Intranasal delivery of influenza rNP adjuvanted with c-di-AMP induces strong humoral and cellular immune responses and provides protection against virus challenge.Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides.The mucosal adjuvant cyclic di-GMP enhances antigen uptake and selectively activates pinocytosis-efficient cells in vivo.Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine.Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells.Cyclic di-nucleotides: new era for small molecules as adjuvants.The mucosal vaccine quandary: intranasal vs. sublingual immunization against influenza.Sensing the messenger: the diverse ways that bacteria signal through c-di-GMP.Systematic identification of small molecule adjuvants.Adjuvant immunotherapies as a novel approach to bacterial infections.Intranasal formulations: promising strategy to deliver vaccines.Modes of Action for Mucosal Vaccine Adjuvants.Transient expression of hemagglutinin antigen from low pathogenic avian influenza A (H7N7) in Nicotiana benthamiana.Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in MiceIdentification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization.cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue.A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination.STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection.Enhanced immunostimulatory activity of cyclic dinucleotides on mouse cells when complexed with a cell-penetrating peptide or combined with CpG.MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.
P2860
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P2860
Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@ast
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@en
type
label
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@ast
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@en
prefLabel
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@ast
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@en
P2093
P1433
P1476
Intranasal c-di-GMP-adjuvanted ...... ic antibody responses in mice.
@en
P2093
Abdullah S Madhun
Carlos A Guzman
Jane Kristin Nøstbakken
Jessica Chichester
Lars R Haaheim
Rebecca J Cox
Thomas Ebensen
Vidadi Yusibov
P304
P356
10.1016/J.VACCINE.2011.04.094
P407
P577
2011-05-18T00:00:00Z