CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.
about
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.RZZ and Mad1 dynamics in Drosophila mitosis.A maternal effect rough deal mutation suggests that multiple pathways regulate Drosophila RZZ kinetochore recruitment.How the SAC gets the axe: Integrating kinetochore microtubule attachments with spindle assembly checkpoint signaling.Signalling dynamics in the spindle checkpoint response.Structure of the RZZ complex and molecular basis of its interaction with Spindly.A Molecular View of Kinetochore Assembly and Function.Regulation of mitotic progression by the spindle assembly checkpointThe CENP-T C-terminus is exclusively proximal to H3.1 and not to H3.2 or H3.3.Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochoresOverexpression of the E2F target gene CENPI promotes chromosome instability and predicts poor prognosis in estrogen receptor-positive breast cancer.A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.Spindle assembly checkpoint satisfaction occurs via end-on but not lateral attachments under tension.DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling.CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres.The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.The spindle checkpoint’s on-off switch.MAD1: Kinetochore Receptors and Catalytic Mechanisms.CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response
P2860
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P2860
CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CENP-I and Aurora B act as a m ...... kinetochore attachment status.
@ast
CENP-I and Aurora B act as a m ...... kinetochore attachment status.
@en
type
label
CENP-I and Aurora B act as a m ...... kinetochore attachment status.
@ast
CENP-I and Aurora B act as a m ...... kinetochore attachment status.
@en
prefLabel
CENP-I and Aurora B act as a m ...... kinetochore attachment status.
@ast
CENP-I and Aurora B act as a m ...... kinetochore attachment status.
@en
P2860
P356
P1476
CENP-I and Aurora B act as a m ...... kinetochore attachment status
@en
P2093
Daniel R Matson
P2860
P304
P356
10.1083/JCB.201307137
P407
P577
2014-05-01T00:00:00Z