Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport - Test2 - elhamkhani - TriplyDB

Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport

Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport

http://www.wikidata.org/entity/Q30419713

about

Circovirus transport proceeds via direct interaction of the cytoplasmic dynein IC1 subunit with the viral capsid protein Axonal transport: cargo-specific mechanisms of motility and regulation Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling.Distinct functional roles of cytoplasmic dynein defined by the intermediate chain isoforms.The neurotrophin receptor signaling endosome: Where trafficking meets signaling.Live cell imaging reveals differential modifications to cytoplasmic dynein properties by phospho- and dephosphomimic mutations of the intermediate chain 2C S84.Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions Epidermal growth factor stimulates extracellular-signal regulated kinase phosphorylation of a novel site on cytoplasmic Dynein intermediate chain 2 Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes.Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease.Cytoplasmic dynein and early endosome transport Neurotrophic Effects of Mu Bie Zi (Momordica cochinchinensis) Seed Elucidated by High-Throughput Screening of Natural Products for NGF Mimetic Effects in PC-12 Cells.Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex Non-Cell-Autonomous Regulation of Retrograde Motoneuronal Axonal Transport in an SBMA Mouse Model Neuronal signaling through endocytosis.IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking Integrated regulation of motor-driven organelle transport by scaffolding proteins.The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.Biogenesis and function of the NGF/TrkA signaling endosome A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation.Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor.GSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility Neurotrophin signaling endosomes: biogenesis, regulation, and functions.Regulation of dynein-dynactin-driven vesicular transport.Spatial-specific functions in retrograde neuronal signalling.A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV)Kalirin is required for BDNF-TrkB stimulated neurite outgrowth and branching.The histone deacetylase inhibitor cambinol prevents acidic pHe-induced anterograde lysosome trafficking independently of sirtuin activity.Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2.Global Identification of ERK Substrates by Phosphoproteomics Based on IMAC and 2D-DIGE.Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus.DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy.Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS.Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors.

P2860

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P2860

Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport

http://www.wikidata.org/entity/Q30419713

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Trk activation of the ERK1/2 k ...... or retrograde axonal transport

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Trk activation of the ERK1/2 k ...... or retrograde axonal transport

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type

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Trk activation of the ERK1/2 k ...... or retrograde axonal transport

@ast

Trk activation of the ERK1/2 k ...... or retrograde axonal transport

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prefLabel

Trk activation of the ERK1/2 k ...... or retrograde axonal transport

@ast

Trk activation of the ERK1/2 k ...... or retrograde axonal transport

@en

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JNEUROSCI.5599-11.2012

P1433

Journal of Neuroscience

P1476

Trk activation of the ERK1/2 k ...... or retrograde axonal transport

@en

P2093

Andrew D Catling

http://www.w3.org/2001/XMLSchema#string

Christopher D Deppmann

http://www.w3.org/2001/XMLSchema#string

David J Mitchell

http://www.w3.org/2001/XMLSchema#string

Donald F Hunt

http://www.w3.org/2001/XMLSchema#string

Dong Suo

http://www.w3.org/2001/XMLSchema#string

Erin D Jeffery

http://www.w3.org/2001/XMLSchema#string

Jonathan C Trinidad

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Juyeon Park

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K Kevin Pfister

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Kevin W-H Lo

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P2860

Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human

Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation

Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment.

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

The selectivity of protein kinase inhibitors: a further update

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

Neurotrophin-regulated signalling pathways

Genetic analysis of the cytoplasmic dynein subunit families.

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

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15495-15510

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scholarly article

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10.1523/JNEUROSCI.5599-11.2012

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P433

44

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P478

32

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Jeffrey Shabanowitz

Ashok K. Pullikuth

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2012-10-01T00:00:00Z

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23115187

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P921

phosphorylation

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3500848

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