β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy - Test2 - elhamkhani - TriplyDB

β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy

β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy

http://www.wikidata.org/entity/Q30427521

about

β1 Integrins as Therapeutic Targets to Disrupt Hallmarks of Cancer Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy Mechanosensitivity and compositional dynamics of cell-matrix adhesions β1 and β4 integrins: from breast development to clinical practice FAK in cancer: mechanistic findings and clinical applications Cortactin as a target for FAK in the regulation of focal adhesion dynamics BEMER Electromagnetic Field Therapy Reduces Cancer Cell Radioresistance by Enhanced ROS Formation and Induced DNA Damage High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients SRChing for the substrates of Src.Microenvironmental regulation of therapeutic response in cancer Direct evidence for cell adhesion-mediated radioresistance (CAM-RR) on the level of individual integrin β1 clusters.RGD-Binding Integrins in Head and Neck Cancers.RAD9 enhances radioresistance of human prostate cancer cells through regulation of ITGB1 protein levels.Targeted iron-oxide nanoparticle for photodynamic therapy and imaging of head and neck cancer Genome-wide gene expression analysis in cancer cells reveals 3D growth to affect ECM and processes associated with cell adhesion but not DNA repair.Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway.Biodistribution Study of Nanoparticle Encapsulated Photodynamic Therapy Drugs Using Multispectral Imaging Marine bromophenol bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane inhibits the proliferation, migration, and invasion of hepatocellular carcinoma cells via modulating β1-integrin/FAK signaling.The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated α2M The traditional Tibetan medicine Yukyung Karne exhibits a potent anti-metastatic activity by inhibiting the epithelial to mesenchymal transition and cell migration.Acquisition of epithelial-mesenchymal transition phenotype in the tamoxifen-resistant breast cancer cell: a new role for G protein-coupled estrogen receptor in mediating tamoxifen resistance through cancer-associated fibroblast-derived fibronectin a Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro.Focal adhesion-chromatin linkage controls tumor cell resistance to radio- and chemotherapy The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.Cell-ECM interactions control DDR.Comprehensive analysis of signal transduction in three-dimensional ECM-based tumor cell cultures Integr(at)in(g) EGFR therapy in HNSCC 3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation.ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation.The effects of CEP-37440, an inhibitor of focal adhesion kinase, in vitro and in vivo on inflammatory breast cancer cells Efficacy of Beta1 Integrin and EGFR Targeting in Sphere-Forming Human Head and Neck Cancer Cells.NF-κB regulates radioresistance mediated by β1-integrin in three-dimensional culture of breast cancer cells.The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour Focal adhesion kinase: predictor of tumour response and risk factor for recurrence after neoadjuvant chemoradiation in rectal cancer.Epigenetic modulation of signal transduction pathways in HPV-associated HNSCC.β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation.APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM.Targeted drugs in combination with radiotherapy for the treatment of solid tumors: current state and future developments.Molecular mechanisms of low dose ionizing radiation-induced hormesis, adaptive responses, radioresistance, bystander effects, and genomic instability.

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P2860

β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy

http://www.wikidata.org/entity/Q30427521

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

@ast

β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

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type

label

β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

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β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

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prefLabel

β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

@ast

β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

@en

P1433

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P1433

Journal of Clinical Investigation

P1476

β₁Integrin/FAK/cortactin signa ...... cer resistance to radiotherapy

@en

P2093

Anna Shevchenko

http://www.w3.org/2001/XMLSchema#string

Kristin Gurtner

http://www.w3.org/2001/XMLSchema#string

Stephanie Hehlgans

http://www.w3.org/2001/XMLSchema#string

Veit Sandfort

http://www.w3.org/2001/XMLSchema#string

Yvonne Deuse

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P2860

Hallmarks of Cancer: The Next Generation

BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Integrins: bidirectional, allosteric signaling machines

Cortactin: coupling membrane dynamics to cortical actin assembly

Signalling via integrins: implications for cell survival and anticancer strategies

Exploring the role of cancer stem cells in radioresistance

Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia

Ligand bound beta1 integrins inhibit procaspase-8 for mediating cell adhesion-mediated drug and radiation resistance in human leukemia cells

P304

1529-1540

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scholarly article

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10.1172/JCI61350

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4

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P478

122

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Michael Baumann

Mechthild Krause

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2012-03-01T00:00:00Z

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22378044

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P921

radiation therapy

P932

3314473

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