Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease.
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Regulation of neutrophil function by adenosine.The role of adenosine signaling in sickle cell therapeuticsPatrolling monocytes control tumor metastasis to the lung.Advances in sickle cell therapies in the hydroxyurea eraAdenosine receptors as drug targets--what are the challenges?The immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation.Lung vaso-occlusion in sickle cell disease mediated by arteriolar neutrophil-platelet microemboli.Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expressionPurinergic signaling during inflammation.Adenosine signaling during acute and chronic disease statesExtracellular nucleotide and nucleoside signaling in vascular and blood diseaseA humanized monoclonal antibody specific for invariant Natural Killer T (iNKT) cells for in vivo depletionElevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activityTargeting iNKT cells for the treatment of sickle cell disease.IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity.Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management.Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo.NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell diseaseInflammatory targets of therapy in sickle cell disease.Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease.Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenosonTranscription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.Detrimental effects of adenosine signaling in sickle cell disease.Adenosine influences myeloid cells to inhibit aeroallergen sensitization.Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model.NF-κB is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptorsExtracellular hemin crisis triggers acute chest syndrome in sickle miceHepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure.Ischemia and reperfusion--from mechanism to translation.Perioperative organ injury.CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.Not simply misshapen red cells: multimolecular and cellular events in sickle vaso-occlusionRegulation of leukocyte function by adenosine receptors.Adenosine receptor targeting in health and disease.Emerging drugs for chronic obstructive pulmonary disease.Adenosine signaling in normal and sickle erythrocytes and beyond.Regulation of lymphocyte function by adenosine.Role of type 1 natural killer T cells in pulmonary immunity.Purinergic signalling and immune cells.
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P2860
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@ast
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@en
type
label
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@ast
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@en
prefLabel
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@ast
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@en
P2860
P1433
P1476
Adenosine A2A receptors induce ...... mice with sickle cell disease.
@en
P2093
Joel Linden
Kori L Wallace
P2860
P304
P356
10.1182/BLOOD-2010-06-290643
P407
P577
2010-08-26T00:00:00Z