Enhancers are major targets for murine leukemia virus vector integration - Test2 - elhamkhani - TriplyDB

Enhancers are major targets for murine leukemia virus vector integration

Enhancers are major targets for murine leukemia virus vector integration

http://www.wikidata.org/entity/Q30429881

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Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection Retroviral DNA Integration Structural and sequencing analysis of local target DNA recognition by MLV integrase.Structural basis for spumavirus GAG tethering to chromatin Novel principles of gamma-retroviral insertional transcription activation in murine leukemia virus-induced end-stage tumors.Molecular mechanisms of retroviral integration site selection.HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells Quantitative shearing linear amplification polymerase chain reaction: an improved method for quantifying lentiviral vector insertion sites in transplanted hematopoietic cell systems Key determinants of target DNA recognition by retroviral intasomes.Characterization of Equine Infectious Anemia Virus Integration in the Horse Genome Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites.Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes.Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction.Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility.Dynamic Transcriptional and Epigenetic Regulation of Human Epidermal Keratinocyte Differentiation.Sites of retroviral DNA integration: From basic research to clinical applications What Integration Sites Tell Us about HIV Persistence LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes.Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes Generation of transgenic marmosets expressing genetically encoded calcium indicators.Chromatin states shape insertion profiles of the piggyBac, Tol2 and Sleeping Beauty transposons and murine leukemia virus.Integration site and clonal expansion in human chronic retroviral infection and gene therapy.Viral Vectors: The Road to Reducing Genotoxicity.Integration site selection by retroviruses and transposable elements in eukaryotes.Hotspots of MLV integration in the hematopoietic tumor genome Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side.Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency.Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy.Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions.Transcriptional, epigenetic and retroviral signatures identify regulatory regions involved in hematopoietic lineage commitment.Differences in vector-genome processing and illegitimate integration of non-integrating lentiviral vectors BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements.Interactions between Retroviruses and the Host Cell Genome.Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers.CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level.Cellular and molecular mechanisms of HIV-1 integration targeting.Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors.

P2860

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P2860

Enhancers are major targets for murine leukemia virus vector integration

http://www.wikidata.org/entity/Q30429881

description

2014 nî lūn-bûn

@nan

2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Enhancers are major targets for murine leukemia virus vector integration

@ast

Enhancers are major targets for murine leukemia virus vector integration

@en

type

label

Enhancers are major targets for murine leukemia virus vector integration

@ast

Enhancers are major targets for murine leukemia virus vector integration

@en

prefLabel

Enhancers are major targets for murine leukemia virus vector integration

@ast

Enhancers are major targets for murine leukemia virus vector integration

@en

P1433

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P1476

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P2860

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P932

Q30429881-2B0D043B-9E9B-4EA5-833F-883CD5AAC5EE

P356

P1433

Journal of Virology

P1476

Enhancers are major targets for murine leukemia virus vector integration

@en

P2093

Andrea L Ferris

http://www.w3.org/2001/XMLSchema#string

Geoff Symonds

http://www.w3.org/2001/XMLSchema#string

Harry L Malech

http://www.w3.org/2001/XMLSchema#string

Ling Su

http://www.w3.org/2001/XMLSchema#string

Narda Theobald

http://www.w3.org/2001/XMLSchema#string

Suk See De Ravin

http://www.w3.org/2001/XMLSchema#string

Susan M Pond

http://www.w3.org/2001/XMLSchema#string

Uimook Choi

http://www.w3.org/2001/XMLSchema#string

Xiaolin Wu

http://www.w3.org/2001/XMLSchema#string

P2860

Model-based analysis of ChIP-Seq (MACS)

Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes

High-resolution profiling of histone methylations in the human genome

Selective recognition of acetylated histones by bromodomain proteins visualized in living cells

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

BEDTools: a flexible suite of utilities for comparing genomic features.

Mapping and analysis of chromatin state dynamics in nine human cell types

Functions of site-specific histone acetylation and deacetylation

P304

4504-4513

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.00011-14

http://www.w3.org/2001/XMLSchema#string

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

88

http://www.w3.org/2001/XMLSchema#string

P50

Michael Poidinger

Janet L. Macpherson

Stephen H. Hughes

P577

2014-02-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

260117950

http://www.w3.org/2001/XMLSchema#string

P698

24501411

http://www.w3.org/2001/XMLSchema#string

P921

vector-borne disease

P932

3993722

http://www.w3.org/2001/XMLSchema#string