A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
about
A mathematical modeling approach to risk assessment for normal and anemic women chronically exposed to carbon monoxide from biomass-fueled cookstovesBinding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitorNeutrophils: Between host defence, immune modulation, and tissue injuryInterferon-beta induces distinct gene expression response patterns in human monocytes versus T cellsGenetic regulation of expression of leukotriene A4 hydrolaseMatrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection.Role of leukotriene A4 hydrolase aminopeptidase in the pathogenesis of emphysema.Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysemaToll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via ExosomesA self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation.Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice.The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers.Profiling of differentially expressed genes using suppression subtractive hybridization in an equine model of chronic asthmaDerivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary diseaseDual anti-inflammatory and selective inhibition mechanism of leukotriene A4 hydrolase/aminopeptidase: insights from comparative molecular dynamics and binding free energy analyses.Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.Efferocytosis and lung diseaseThree cases of previous smokers with rheumatoid arthritis who did not respond to tumor necrosis factor inhibitors were treated successfully with an anti-interleukin-6 receptor antibodyA remarkable activity of human leukotriene A4 hydrolase (LTA4H) toward unnatural amino acidsSIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis.Direct observation of phagocytosis and NET-formation by neutrophils in infected lungs using 2-photon microscopyExome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic backgroundHost-pathogen interplay in the respiratory environment of cystic fibrosis.The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeabilityHeme oxygenase-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated miceIdentification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus.Enzyme Tunnels and Gates As Relevant Targets in Drug Design.A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease.Neutrophils cascading their way to inflammationNeutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastaseProteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis.A Single 9-Colour Flow Cytometric Method to Characterise Major Leukocyte Populations in the Rat: Validation in a Model of LPS-Induced Pulmonary Inflammation.Leukotriene A4 hydrolase haplotype, diet and atherosclerosis: a twin study.Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H.Differential Expression of Inflammation-Related Genes in Children with Down SyndromeChronic Rhinosinusitis without Nasal Polyps.Neutrophils: potential therapeutic targets in tularemia?
P2860
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P2860
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@ast
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@en
type
label
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@ast
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@en
prefLabel
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@ast
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@en
P2093
P2860
P356
P1433
P1476
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation
@en
P2093
Amit Gaggar
Andrew Kinloch
Brett D Noerager
Matthew T Hardison
Patricia L Jackson
Robert J Snelgrove
Steven M Rowe
Suresh Shastry
Yun M Shim
P2860
P356
10.1126/SCIENCE.1190594
P407
P577
2010-09-02T00:00:00Z