Abakavir%D8%A3%D8%A8%D8%A7%D9%83%D8%A7%D9%81%D9%8A%D8%B1%D8%A7%D8%A8%D8%A7%DA%A9%D8%A7%D9%88%DB%8C%D8%B1%E0%A6%85%E0%A7%8D%E0%A6%AF%E0%A6%BE%E0%A6%AC%E0%A6%BE%E0%A6%95%E0%A6%BE%E0%A6%AD%E0%A6%BF%E0%A6%B0Category:AbacavirAbakavirAbacafirAbacavirAbacavirAbacavirAbakaviiriAbacavir%D7%90%D7%91%D7%A7%D7%95%D7%95%D7%99%D7%A8AbakavirAbacavir%E3%82%A2%E3%83%90%E3%82%AB%E3%83%93%E3%83%AB%EC%95%84%EB%B0%94%EC%B9%B4%EB%B9%84%EB%A5%B4%E0%AC%86%E0%AC%AC%E0%AC%BE%E0%AC%95%E0%AC%BE%E0%AC%AD%E0%AC%BF%E0%AC%B0Abakawir%D8%A7%D8%A8%D8%A7%DA%A9%D8%A7%D9%88%D9%8A%D8%B1AbacavirAbacavir%D0%90%D0%B1%D0%B0%D0%BA%D0%B0%D0%B2%D0%B8%D1%80AbakavirAbakavirAbakavirAbakavirAbakavir%E0%B0%85%E0%B0%AC%E0%B0%BE%E0%B0%95%E0%B0%B5%E0%B0%BF%E0%B0%B0%E0%B1%8D%E0%B8%AD%E0%B8%B0%E0%B8%9A%E0%B8%B2%E0%B8%84%E0%B8%B2%E0%B9%80%E0%B8%A7%E0%B8%B5%E0%B8%A2%E0%B8%A3%E0%B9%8C%D0%90%D0%B1%D0%B0%D0%BA%D0%B0%D0%B2%D1%96%D1%80AbacavirQ304330Abacavir%E9%98%BF%E5%B7%B4%E5%8D%A1%E7%B6%AD
about
sameAs
P1855
P3781
Optimizing Pediatric HIV-1 Treatment in Infants With Prophylactic Exposure to Nevirapine, Nairobi, KenyaSHARE: Simple HAART With Abacavir, Reyataz, and EpivirHLA-B*5701 And Hypersensitivity To AbacavirA Simplification Study of Unboosted Reyataz With Epzicom (ASSURE)Fractures Stratified by HIV and Antiretroviral Therapy (ART) StatusPENTA15: Pharmacokinetic Study of Once Versus Twice Daily Abacavir in HIV-1 Infected Children Aged 3 to <36 MonthsLopinavir/r Monotherapy Versus Abacavir/Lamivudine and Lopinavir/r for Limb Fat Recovery in Persons With LipoatrophyA Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c)Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at BirthA Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior TherapyBlood Levels of Abacavir in HIV Infected AdolescentsComparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIVKALETRA Or LEXIVA With Ritonavir Combined With EPIVIR And Abacavir In Naive Subjects Over 48 WeeksCyclosporine A in Combination With Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in HIVPilot Study With Isentress (Raltegravir) and Epzicom (Abacavir/Lamivudine) in Treatment Naive HIV-Infected SubjectsA Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/EmtriRelative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination TabletsStudy of Options for Second-Line Effective Combination Therapy (SELECT)Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET)Effect of Aspirin on Abacavir-induced Platelet Reactivity in HIV-infected PatientsA Prospective, Open-label Trial of Two ABC/3TC Based Regimens in Late Presenter naïve Patients (CD4 <200 Cells/µL)The Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less Than 12 Years of AgeTriumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject DrugsA Trial Comparing GSK1349572 50mg Plus Abacavir/Lamivudine Once Daily to Atripla (Also Called The SINGLE Trial)Estimate The Effect Of Lersivirine On The Pharmacokinetics Of Abacavir/Lamivudine In Healthy SubjectsMulticentre Study To Assess Changes In Bone Mineral Density Of The Switch From Tenofovir To Abacavir In Hiv-1-Infected Subjects With Loss Of Bone Mineral DensityTreatment Options for Protease Inhibitor-exposed ChildrenAntiretroviral Pregnancy Registry (APR)-Risk of Birth DefectsEvaluation of the Bioequivalence of a Combined Formulated TabletNucleoside Switch Pilot for Virologically Controlled HIV Subjects With Decreasing CD4 Cells Who Have Received TDF-based ARV TherapyAbacavir and Lamivudine PK in ChildrenDose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus-1 (HIV-1) Virologic Suppression Followed by Virologic Suppression Maintenance by GSK1265744 Plus RilpivirineStudy of the Antiviral and Immunological Effects of Intensification of Suppressive Antiretroviral Therapy With MaravirocLopinavir/r/ Lamivudine/ Abacavir as an Easy to Use Paediatric FormulationSafety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in HIV-1 Infected, Antiretroviral Treatment-Naïve AdultsSafety and Efficacy of Switching From Regimens Consisting of Boosted Atazanavir or Darunavir Plus Either Emtricitabine/Tenofovir or Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed HIV-1 InfectedA Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Efficacy of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 YearsSafety and Efficacy of Fixed Dose Combination Dolutegravir/Abacavir/Lamivudine FDC Initiated During Acute HIV InfectionStudy to Evaluate the Efficacy of MONotherapy of TiviCAY® Versus a Triple Therapy in HIV-1-infected PatientsBioequivalence and Pharmacokinetic Study of Prurisol™ and Abacavir Sulfate in Healthy Volunteers
P4844
Abacavir/lamivudine/zidovudineAbacavir/dolutegravir/lamivudineabacavir/lamivudineabacavirabacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphateabacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDPabacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+abacavir + AMP => abacavir monophosphate + adenosineabacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate_R-HSA-2161517
P527
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivityInhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitorsAbacavir induced T cell reactivity from drug naïve individuals shares features of allo-immune responsesAbacavir-reactive memory T cells are present in drug naïve individualsAcyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity.High-performance liquid chromatographic assay for abacavir and its two major metabolites in human urine and cerebrospinal fluidHologram QSAR model for the prediction of human oral bioavailability.Antiviral drug allergy.Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potency.Effect of various pyrimidines possessing the 1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl] moiety, able to mimic natural 2'-deoxyribose, on wild-type and mutant hepatitis B virus replication.Inhibition of hepatitis B virus (HBV) replication by pyrimidines bearing an acyclic moiety: effect on wild-type and mutant HBV.Understanding drug hypersensitivity: what to look for when prescribing abacavir.The role of 2',3'-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V).Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.Abacavir prodrugs: microwave-assisted synthesis and their evaluation of anti-HIV activities.
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de-ch
chemische verbinding
@nl
component quimic
@oc
name
Abacavir
@de
Abacavir
@it
Abacavir
@nl
Abacavir
@ro
Abacavir
@vi
Abacavir
@yo
Abakaviiri
@fi
Abakavir
@af
Abakavir
@cs
Abakavir
@id
type
label
Abacavir
@de
Abacavir
@it
Abacavir
@nl
Abacavir
@ro
Abacavir
@vi
Abacavir
@yo
Abakaviiri
@fi
Abakavir
@af
Abakavir
@cs
Abakavir
@id
altLabel
(1S,4R)-4-[2-amino-6-(ciclopropilamino)-9H-purin-9-il]-2-ciclopenteno-1-metanol
@pt-br
136470-78-5
@fr
136470-78-5
@pt-br
1592U89
@pt-br
ABC
@en
ATC code J05AF06
@en
ATCvet code QJ05AF06
@en
Abacavir sulfate
@en
Abacavir
@en
Abacavir
@sk
prefLabel
Abacavir
@de
Abacavir
@it
Abacavir
@nl
Abacavir
@ro
Abacavir
@vi
Abacavir
@yo
Abakaviiri
@fi
Abakavir
@af
Abakavir
@cs
Abakavir
@id