Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori.
about
Structure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pyloriPreclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pyloriResponse to metronidazole and oxidative stress is mediated through homeostatic regulator HsrA (HP1043) in Helicobacter pylori.Synthesis and antimicrobial evaluation of nitazoxanide-based analogues: identification of selective and broad spectrum activityBiological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide.Functional analysis of the RdxA and RdxB nitroreductases of Campylobacter jejuni reveals that mutations in rdxA confer metronidazole resistanceActivation of benznidazole by trypanosomal type I nitroreductases results in glyoxal formationPyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lambliaComparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds.The Helicobacter pylori CZB Cytoplasmic Chemoreceptor TlpD Forms an Autonomous Polar Chemotaxis Signaling Complex That Mediates a Tactic Response to Oxidative Stress.Molecular and Proteomic Analysis of Levofloxacin and Metronidazole Resistant Helicobacter pylori.Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines.Maximizing bactericidal activity with combinations of bioreduced drugs.Contingency nature of Helicobacter bizzozeronii oxygen-insensitive NAD(P)H-nitroreductase (HBZC1_00960) and its role in metronidazole resistance.Microevolution of a zoonotic Helicobacter population colonizing the stomach of a human host before and after failed treatment.Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori.FrxA is an S-nitrosoglutathione reductase enzyme that contributes to Helicobacter pylori pathogenicity.Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2).A review on metronidazole: an old warhorse in antimicrobial chemotherapy.Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs.
P2860
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P2860
Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@ast
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@en
type
label
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@ast
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@en
prefLabel
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@ast
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@en
P2860
P1433
P1476
Characterization of the NAD(P) ...... uctase of Helicobacter pylori.
@en
P2093
Avery Goodwin
Paul S Hoffman
P2860
P304
P356
10.1111/J.1742-4658.2009.07060.X
P407
P577
2009-05-07T00:00:00Z