Behavioral deficits in an Angelman syndrome model: effects of genetic background and age. - Test2 - elhamkhani - TriplyDB

Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducing Arc expression.Sleep, plasticity and the pathophysiology of neurodevelopmental disorders: the potential roles of protein synthesis and other cellular processes.Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis.Disruption of the LTD dialogue between the cerebellum and the cortex in Angelman syndrome model: a timing hypothesis.Truncation of Ube3a-ATS unsilences paternal Ube3a and ameliorates behavioral defects in the Angelman syndrome mouse model Ube3a imprinting impairs circadian robustness in Angelman syndrome models Towards a therapy for Angelman syndrome by targeting a long non-coding RNA.Imbalanced mechanistic target of rapamycin C1 and C2 activity in the cerebellum of Angelman syndrome mice impairs motor function.Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model.Angelman Syndrome.Of mothers and myelin: Aberrant myelination phenotypes in mouse model of Angelman syndrome are dependent on maternal and dietary influences Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact.Forniceal deep brain stimulation rescues hippocampal memory in Rett syndrome mice Potential therapeutic approaches for Angelman syndrome.Impaired burrowing is the most prominent behavioral deficit of aging htau mice.The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer.Activity-dependent changes in MAPK activation in the Angelman Syndrome mouse model.Angelman syndrome: review of clinical and molecular aspects.Phenotypic plasticity and the perception-action-cognition-environment paradigm in neurodevelopmental genetic disorders.Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice.Diet-induced obesity prolongs neuroinflammation and recruits CCR2(+) monocytes to the brain following herpes simplex virus (HSV)-1 latency in mice.Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism.Angelman syndrome: Current and emerging therapies in 2016.Standardized experiments in mutant mice reveal behavioural similarity on 129S5 and C57BL/6J backgrounds.mTORC1-S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome mice Decreased Axon Caliber Underlies Loss of Fiber Tract Integrity, Disproportional Reductions in White Matter Volume, and Microcephaly in Angelman Syndrome Model Mice.Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.Pharmacological therapies for Angelman syndrome.Hypersociability in the Angelman syndrome mouse model.Enhanced Nociception in Angelman Syndrome Model Mice.Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome.Touchscreen learning deficits in Ube3a, Ts65Dn and Mecp2 mouse models of neurodevelopmental disorders with intellectual disabilities.Reversal of reduced parvalbumin neurons in hippocampus and amygdala of Angelman syndrome model mice by chronic treatment of fluoxetine.An essential role for UBE2A/HR6A in learning and memory and mGLUR-dependent long-term depression.Enhanced operant extinction and prefrontal excitability in a mouse model of Angelman syndrome.Impaired Neurite Contact Guidance in Ubiquitin Ligase E3a (Ube3a)-Deficient Hippocampal Neurons on Nanostructured Substrates.Amelioration of Muscle and Nerve Pathology in LAMA2 Muscular Dystrophy by AAV9-Mini-Agrin.Mammalian TRIM67 Functions in Brain Development and Behavior.Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

http://www.wikidata.org/entity/Q30440078

description

2013 nî lūn-bûn

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2013年の論文

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name

Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age.

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J.BBR.2012.12.052

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Behavioural Brain Research

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Behavioral deficits in an Angelman syndrome model: effects of genetic background and age

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Andrew J Burns

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Benjamin D Philpot

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Koji Yashiro

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Natallia V Riddick

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Randal J Nonneman

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Sheryl S Moy

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Thorfinn T Riday

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Viktoriya D Nikolova

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P2860

UBE3A/E6-AP mutations cause Angelman syndrome

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

Inbred strain differences in prepulse inhibition of the mouse startle response

Developments of a water-maze procedure for studying spatial learning in the rat

Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains

Impaired sociability and cognitive function in Nrcam-null mice.

Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a

Normal social seeking behavior, hypoactivity and reduced exploratory range in a mouse model of Angelman syndrome

Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors

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79-90

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10.1016/J.BBR.2012.12.052

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243

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Hsien-Sung Huang

Lorinda K Baker

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2013-01-04T00:00:00Z

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