Widespread alterations of alpha-synuclein in multiple system atrophy - Test2 - elhamkhani - TriplyDB

Widespread alterations of alpha-synuclein in multiple system atrophy

Widespread alterations of alpha-synuclein in multiple system atrophy

http://www.wikidata.org/entity/Q30444927

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p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies Multiple system atrophy: cellular and molecular pathology.p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy Dorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosis Exploring myelin dysfunction in multiple system atrophy The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Animal modeling an oligodendrogliopathy--multiple system atrophy Lewy bodies and parkinsonism in families with parkin mutations Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve Clinicopathologic variability of the GRN A9D mutation, including amyotrophic lateral sclerosis Progression and prognosis in multiple system atrophy: an analysis of 230 Japanese patients.Biochemical characterization of the core structure of alpha-synuclein filaments.alpha-Synuclein affects the MAPK pathway and accelerates cell death.The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease.Glial degeneration and reactive gliosis in alpha-synucleinopathies: the emerging concept of primary gliodegeneration.Glucocerebrosidase mutations in 108 neuropathologically confirmed cases of multiple system atrophy Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure.Distinct region-specific alpha-synuclein oligomers in A53T transgenic mice: implications for neurodegeneration.Multiple system atrophy: a sporadic synucleinopathy.α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body Disorders Neuropathology of synuclein aggregates.The neuropathology, pathophysiology and genetics of multiple system atrophy.REM sleep behavior disorder in Parkinson's disease and dementia with Lewy bodies.Dysautonomia in Parkinson disease ER stress response plays an important role in aggregation of α-synuclein Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers.Abnormalities of the nucleus and nuclear inclusions in neurodegenerative disease: a work in progress.Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synuclein.The symptomatic treatment of multiple system atrophy.Genetics of parkinsonism.Are pathological lesions in neurodegenerative disorders the cause or the effect of the degeneration?Misfolded, protease-resistant proteins in animal models and human neurodegenerative disease SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening.E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology.Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model Non-Alzheimer's disease dementias: anatomic, clinical, and molecular correlates.α-Synuclein pathology accumulates in sacral spinal visceral sensory pathways.Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies

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P2860

Widespread alterations of alpha-synuclein in multiple system atrophy

http://www.wikidata.org/entity/Q30444927

description

1999 nî lūn-bûn

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1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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1999 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Widespread alterations of alpha-synuclein in multiple system atrophy

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Widespread alterations of alpha-synuclein in multiple system atrophy

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Widespread alterations of alpha-synuclein in multiple system atrophy

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Widespread alterations of alpha-synuclein in multiple system atrophy

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Widespread alterations of alpha-synuclein in multiple system atrophy

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Widespread alterations of alpha-synuclein in multiple system atrophy

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The American Journal of Pathology

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Widespread alterations of alpha-synuclein in multiple system atrophy

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C D'Amato

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Protein measurement with the Folin phenol reagent

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system.

Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990.

Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).

Myelin degeneration in multiple system atrophy detected by unique antibodies.

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.

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John Anthony Hardy

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