Search for cyclodextrin-based inhibitors of anthrax toxins: synthesis, structural features, and relative activities.
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Obstructing toxin pathways by targeted pore blockageTailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxicationInhibition of S. aureus alpha-hemolysin and B. anthracis lethal toxin by beta-cyclodextrin derivatives.Blockage of anthrax PA63 pore by a multicharged high-affinity toxin inhibitor.Theory for polymer analysis using nanopore-based single-molecule mass spectrometryClick synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogensNew developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis.Channel-forming bacterial toxins in biosensing and macromolecule deliverySmall molecule inhibitors of Bacillus anthracis protective antigen proteolytic activation and oligomerization.Designed azolopyridinium salts block protective antigen pores in vitro and protect cells from anthrax toxin.Cyclodextrin derivatives as anti-infectives.Designing inhibitors of anthrax toxinSymmetry requirements for effective blocking of pore-forming toxins: comparative study with alpha-, beta-, and gamma-cyclodextrin derivatives.Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins.Kinetics and thermodynamics of binding reactions as exemplified by anthrax toxin channel blockage with a cationic cyclodextrin derivative.In vivo efficacy of beta-cyclodextrin derivatives against anthrax lethal toxinNovel inhibitors of bacterial virulence: development of 5,6-dihydrobenzo[h]quinazolin-4(3H)-ones for the inhibition of group A streptococcal streptokinase expression.Inhibiting bacterial toxins by channel blockage.New insights into the pathogenesis and treatment of anthrax toxin-induced shock.Potential biological targets of Bacillus anthracis in anti-infective approaches against the threat of bioterrorism.Theory of polymer-nanopore interactions refined using molecular dynamics simulations.Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study.Targeting bacterial toxins.An overview of investigational toxin-directed therapies for the adjunctive management of Bacillus anthracis infection and sepsis.Multivalent Inhibitors of Channel-Forming Bacterial Toxins.Cationic PAMAM dendrimers as pore-blocking binary toxin inhibitors.Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1Tailored cyclodextrin pore blocker protects mammalian cells from clostridium difficile binary toxin CDT.Single-molecule interrogation of a bacterial sugar transporter allows the discovery of an extracellular inhibitor.Access to Versatile β-Cyclodextrin Scaffolds through Guest-Mediated Monoacylation.
P2860
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P2860
Search for cyclodextrin-based inhibitors of anthrax toxins: synthesis, structural features, and relative activities.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Search for cyclodextrin-based ...... ures, and relative activities.
@ast
Search for cyclodextrin-based ...... ures, and relative activities.
@en
type
label
Search for cyclodextrin-based ...... ures, and relative activities.
@ast
Search for cyclodextrin-based ...... ures, and relative activities.
@en
prefLabel
Search for cyclodextrin-based ...... ures, and relative activities.
@ast
Search for cyclodextrin-based ...... ures, and relative activities.
@en
P2093
P2860
P356
P1476
Search for cyclodextrin-based ...... ures, and relative activities.
@en
P2093
Adiamseged Yohannes
Ekaterina M Nestorovich
Frank Schmidtmann
Sergey M Bezrukov
Sidney M Hecht
Tanisha M Robinson
Vladimir A Karginov
P2860
P304
P356
10.1128/AAC.00693-06
P407
P577
2006-09-18T00:00:00Z