Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells. - Test2 - elhamkhani - TriplyDB

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.

http://www.wikidata.org/entity/Q30445485

about

Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions Cholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activation SOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokines The role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECs Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Much ado about adenosine: adenosine synthesis and function in regulatory T cell biology.Suppression of inflammatory and immune responses by the A(2A) adenosine receptor: an introduction.Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.Induction of leptin resistance by activation of cAMP-Epac signaling.Ghrelin induces leptin resistance by activation of suppressor of cytokine signaling 3 expression in male rats: implications in satiety regulation Regulation of PC12 cell differentiation by cAMP signaling to ERK independent of PKA: do all the connections add up?Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1 Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses The future of EPAC-targeted therapies: agonism versus antagonism Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes.Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1.Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.Exchange protein directly activated by cAMP modulates regulatory T-cell-mediated immunosuppression Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA Effects of Controlled Cortical Impact on the Mouse Brain Vasculome.Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells.Chronic lymphocytic leukemia and B and T cells differ in their response to cyclic nucleotide phosphodiesterase inhibitors.EPAC proteins transduce diverse cellular actions of cAMP.Prostacyclin inhibits IFN-gamma-stimulated cytokine expression by reduced recruitment of CBP/p300 to STAT1 in a SOCS-1-independent manner.Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Design and application of locally delivered agonists of the adenosine A(2A) receptor.Regulation of the inflammatory response of vascular endothelial cells by EPAC1.Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP).Cavin-1: caveolae-dependent signalling and cardiovascular disease.Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression.Characterization of the roles of suppressor of cytokine signaling-3 in prostate cancer development and progression.Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes.Activation of protein kinase Calpha by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein beta-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells.

P2860

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P2860

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.

http://www.wikidata.org/entity/Q30445485

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Exchange protein activated by ...... in vascular endothelial cells.

@ast

Exchange protein activated by ...... in vascular endothelial cells.

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type

label

Exchange protein activated by ...... in vascular endothelial cells.

@ast

Exchange protein activated by ...... in vascular endothelial cells.

@en

prefLabel

Exchange protein activated by ...... in vascular endothelial cells.

@ast

Exchange protein activated by ...... in vascular endothelial cells.

@en

P1433

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Q30445485-8560F0DD-BA98-4D0F-AC05-2C4BB8D14C5D

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P2860

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Q30445485-1D633B75-F9B4-4382-91D6-74F9A6399425

Q30445485-1ED0F6EF-8BE1-4F7D-AA8C-F12C968405BA

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P1433

Molecular and Cellular Biology

P1476

Exchange protein activated by ...... in vascular endothelial cells.

@en

P2093

Claire Rutherford

http://www.w3.org/2001/XMLSchema#string

Gillian R Milne

http://www.w3.org/2001/XMLSchema#string

Hayley D Woolson

http://www.w3.org/2001/XMLSchema#string

Timothy M Palmer

http://www.w3.org/2001/XMLSchema#string

William A Sands

http://www.w3.org/2001/XMLSchema#string

P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons

The cloning of a family of genes that encode the melanocortin receptors

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B

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6333-6346

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scholarly article

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10.1128/MCB.00207-06

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P433

17

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P478

26

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P577

2006-09-01T00:00:00Z

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6872624

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16914720

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P932

1592846

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