Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.
about
The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cellsA potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.Initiation sites are distributed at frequent intervals in the Chinese hamster dihydrofolate reductase origin of replication but are used with very different efficienciesThe dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity.The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation.Cdc45 limits replicon usage from a low density of preRCs in mammalian cellsA winding road to origin discoverySpecific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication.Characterizing replication intermediates in the amplified CHO dihydrofolate reductase domain by two novel gel electrophoretic techniques.Composite patterns in neutral/neutral two-dimensional gels demonstrate inefficient replication origin usage.The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sitesLagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase originAttachment to the nuclear matrix mediates specific alterations in chromatin structure.DNA replication origins in the Schizosaccharomyces pombe genome.Eukaryotic DNA replication.Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.Site-specific initiation of DNA replication in Xenopus egg extract requires nuclear structure.High-resolution mapping of the origin of DNA replication in the hamster dihydrofolate reductase gene domain by competitive PCR.Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.An origin of replication and a centromere are both needed to establish a replicative plasmid in the yeast Yarrowia lipolyticaShort DNA fragments without sequence similarity are initiation sites for replication in the chromosome of the yeast Yarrowia lipolyticaReplication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis.The Chinese hamster dihydrofolate reductase replication origin beta is active at multiple ectopic chromosomal locations and requires specific DNA sequence elements for activity.DNA replication initiates non-randomly at multiple sites near the c-myc gene in HeLa cellsoriGNAI3: a narrow zone of preferential replication initiation in mammalian cells identified by 2D gel and competitive PCR replicon mapping techniques.Multiple mechanisms contribute to Schizosaccharomyces pombe origin recognition complex-DNA interactions.The Chinese hamster dihydrofolate reductase replication origin decision point follows activation of transcription and suppresses initiation of replication within transcription units.
P2860
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P2860
Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Replication initiation sites a ...... ihydrofolate reductase domain.
@ast
Replication initiation sites a ...... ihydrofolate reductase domain.
@en
type
label
Replication initiation sites a ...... ihydrofolate reductase domain.
@ast
Replication initiation sites a ...... ihydrofolate reductase domain.
@en
prefLabel
Replication initiation sites a ...... ihydrofolate reductase domain.
@ast
Replication initiation sites a ...... ihydrofolate reductase domain.
@en
P2093
P2860
P356
P1476
Replication initiation sites a ...... ihydrofolate reductase domain.
@en
P2093
J L Hamlin
J P Vaughn
P A Dijkwel
P2860
P304
P356
10.1093/NAR/22.23.4989
P407
P577
1994-11-01T00:00:00Z