Cytoplasmic death signal triggered by SRC-mediated phosphorylation of the adenovirus E4orf4 protein.
about
Regulation of human adenovirus alternative RNA splicing by the adenoviral L4-33K and L4-22K proteinsAgonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signallingMechanisms of cancer cell killing by the adenovirus E4orf4 proteinThe Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling PathwayAdenovirus E4orf4 hijacks rho GTPase-dependent actin dynamics to kill cells: a role for endosome-associated actin assembly.Localization and importance of the adenovirus E4orf4 protein during lytic infectionRegulation of cell death by recycling endosomes and golgi membrane dynamics via a pathway involving Src-family kinases, Cdc42 and Rab11a.The cytosolic tail of the Golgi apyrase Ynd1 mediates E4orf4-induced toxicity in Saccharomyces cerevisiae.Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein.A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases.The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.Viral genes as oncolytic agents for cancer therapy.Adenovirus E4orf4 protein-induced death of p53-/- H1299 human cancer cells follows a G1 arrest of both tetraploid and diploid cells due to a failure to initiate DNA synthesis.JNK-mediated phosphorylation of paxillin in adhesion assembly and tension-induced cell death by the adenovirus death factor E4orf4.YND1 interacts with CDC55 and is a novel mediator of E4orf4-induced toxicity.The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes.Activation of adenovirus type 2 early region 4 ORF4 cytoplasmic death function by direct binding to Src kinase domain.EGFR-mediated apoptosis via STAT3.
P2860
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P2860
Cytoplasmic death signal triggered by SRC-mediated phosphorylation of the adenovirus E4orf4 protein.
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@ast
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@en
type
label
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@ast
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@en
prefLabel
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@ast
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@en
P2093
P2860
P1476
Cytoplasmic death signal trigg ...... the adenovirus E4orf4 protein.
@en
P2093
Claudia Champagne
Josée N Lavoie
Marie-Claude Gingras
Mélanie Roy
P2860
P356
10.1128/MCB.22.1.41-56.2002
P407
P577
2002-01-01T00:00:00Z