Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
about
Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms.Genetic predisposition to peripheral nerve neoplasia: diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromesCo-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity.ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1)PleiotRHOpic: Rho pathways are essential for all stages of Neural Crest development.TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions.Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST).Wilms' tumor gene 1 (WT1) silencing inhibits proliferation of malignant peripheral nerve sheath tumor sNF96.2 cell line.Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis.Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesisThe Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenanceNeuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problemsMerlin, the NF2 gene product.CNS Tumors in Neurofibromatosis.Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis.Identification of candidate genes for devil facial tumour disease tumourigenesis.Clinicopathologic implications of NF1 gene alterations in diffuse gliomasStressing out the Hippo/YAP signaling pathway: toward a new role in Schwann cells.Expression profiling of 519 kinase genes in matched malignant peripheral nerve sheath tumor/plexiform neurofibroma samples is discriminatory and identifies mitotic regulators BUB1B, PBK and NEK2 as overexpressed with transformation.Fatal acute retropharyngeal hemorrhage in neurofibromatosis type 1.[Pathogenesis and molecular pathology of vestibular schwannoma].Superficial malignant peripheral nerve sheath tumor with overlying intradermal melanocytic nevus mimicking spindle cell melanoma.Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome.Soft Tissue Sarcoma Cancer Stem Cells: An Overview
P2860
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P2860
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
@ast
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
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type
label
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
@ast
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
@en
prefLabel
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
@ast
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
@en
P2860
P1476
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
@en
P2860
Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients
Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus
P2888
P304
P356
10.1007/S00401-011-0928-6
P577
2011-12-11T00:00:00Z
P5875
P6179
1045404524