A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.
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Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling NetworksHuman Specific Regulation of the Telomerase Reverse Transcriptase GeneBrain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the futureTelomerase Regulation from Beginning to the EndMutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancersLive Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres.CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice.Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase.Telomerase reactivation in cancers: Mechanisms that govern transcriptional activation of the wild-type vs. mutant TERT promotersEndogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.Enhanced CRISPR/Cas9-mediated biallelic genome targeting with dual surrogate reporter-integrated donors.Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem CellsPop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation.Telomerase and drug resistance in cancer.Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashionTools and strategies for scarless allele replacement in Drosophila using CRISPR/Cas9.Genome editing: the end of the beginning.TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions.CRISPR-based strategies for studying regulatory elements and chromatin structure in mammalian gene control.MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.Control of gene editing by manipulation of DNA repair mechanisms.Insights about genome function from spatial organization of the genome.Anti-cancer binary system activated by bacteriophage HK022 integrase.Application of the CRISPR/Cas9 System to Drug Resistance in Breast Cancer.Telomere Maintenance Mechanisms in Cancer.Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunitsA G-Quadruplex Structure in the Promoter Region of Functions as a Regulatory Element for Gene Expression
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P2860
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.
description
2015 nî lūn-bûn
@nan
2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A novel two-step genome editin ...... tion and TERT gene expression.
@ast
A novel two-step genome editin ...... tion and TERT gene expression.
@en
type
label
A novel two-step genome editin ...... tion and TERT gene expression.
@ast
A novel two-step genome editin ...... tion and TERT gene expression.
@en
prefLabel
A novel two-step genome editin ...... tion and TERT gene expression.
@ast
A novel two-step genome editin ...... tion and TERT gene expression.
@en
P2093
P2860
P1433
P1476
A novel two-step genome editin ...... tion and TERT gene expression.
@en
P2093
Dante R Ascarrunz
Jens C Schmidt
P2860
P2888
P356
10.1186/S13059-015-0791-1
P577
2015-11-10T00:00:00Z
P5875
P6179
1008612431