Acid-sensing ion channels: A new target for pain and CNS diseases
about
pH sensing and regulation in cancerAcid-sensing ion channels in pain and disease.Structure and activity of the acid-sensing ion channelsTwo aspects of ASIC function: Synaptic plasticity and neuronal injury.The dichotomized role for acid sensing ion channels in musculoskeletal pain and inflammationA single amino acid tunes Ca2+ inhibition of brain liver intestine Na+ channel (BLINaC)Physiological and pathological functions of acid-sensing ion channels in the central nervous system.Acid-Sensing Ion Channels and PainAcid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium.Small molecule ion channel match making: a natural fit for new ASIC ligands.Acid-sensing ion channels: trafficking and synaptic function.Binding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a.PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner.Insights into the mechanism of pore opening of acid-sensing ion channel 1a.Spider-venom peptides as therapeutics.ASICs Do Not Play a Role in Maintaining Hyperalgesia Induced by Repeated Intramuscular Acid Injections.Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC).Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding.N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling.ASIC3 channels in multimodal sensory perceptionCyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3.Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions.Selective targeting of ASIC3 using artificial miRNAs inhibits primary and secondary hyperalgesia after muscle inflammationGenome-wide association study identifies two new susceptibility loci for colorectal cancer at 5q23.3 and 17q12 in Han Chinese.Osthole, a herbal compound, alleviates nucleus pulposus-evoked nociceptive responses through the suppression of overexpression of acid-sensing ion channel 3 (ASIC3) in rat dorsal root ganglion.Acid-sensing ion channel 3 deficiency increases inflammation but decreases pain behavior in murine arthritis.Diarylamidines: high potency inhibitors of acid-sensing ion channels.Differential regulation of locomotor activity to acute and chronic cocaine administration by acid-sensing ion channel 1a and 2 in adult mice.Protonation controls ASIC1a activity via coordinated movements in multiple domains.Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a.Modulation of ionotropic glutamate receptors and Acid-sensing ion channels by nitric oxide.Acid-sensing ion channels contribute to neurotoxicity.ASICs Mediate Pain and Inflammation in Musculoskeletal Diseases.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Acidosis counteracts itch tachyphylaxis to consecutive pruritogen exposure dependent on acid-sensing ion channel 3.Acid sensitivity of the spinal dorsal root ganglia C-fiber nociceptors innervating the guinea pig esophagusEndogenous Isoquinoline Alkaloids Agonists of Acid-Sensing Ion Channel Type 3.Three distinct motifs within the C-terminus of acid-sensing ion channel 1a regulate its surface trafficking.Coxsackievirus and adenovirus receptor (CAR) mediates trafficking of acid sensing ion channel 3 (ASIC3) via PSD-95
P2860
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P2860
Acid-sensing ion channels: A new target for pain and CNS diseases
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Acid-sensing ion channels: A new target for pain and CNS diseases
@ast
Acid-sensing ion channels: A new target for pain and CNS diseases
@en
type
label
Acid-sensing ion channels: A new target for pain and CNS diseases
@ast
Acid-sensing ion channels: A new target for pain and CNS diseases
@en
prefLabel
Acid-sensing ion channels: A new target for pain and CNS diseases
@ast
Acid-sensing ion channels: A new target for pain and CNS diseases
@en
P2093
P2860
P1476
Acid-sensing ion channels: A new target for pain and CNS diseases
@en
P2093
John A Wemmie
Kathleen A Sluka
Olivia C Winter
P2860
P304
P577
2009-09-01T00:00:00Z