Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity.
about
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expressionSmall chaperons and autophagy protected neurons from necrotic cell deathPathologies associated with the p53 response.Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons.Neuropeptide Y regulates the hematopoietic stem cell microenvironment and prevents nerve injury in the bone marrow.Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury.The p53 family in nervous system development and disease.MPP+-induces PUMA- and p53-dependent, but ATF3-independent cell death.Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease.Enhanced survival of dopaminergic neuronal transplants in hemiparkinsonian rats by the p53 inactivator PFT-αMitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic modelsPost-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cellsGenetic determinants of neuronal vulnerability to apoptosis.Programmed cell death in Parkinson's diseaseThe beneficial role of thiamine in Parkinson disease.Molecular mechanisms and anti-cancer aspects of the medicinal phytochemicals rocaglamides (=flavaglines).β-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38(MAPK)-p53 Signaling Pathway.Autophagy and p53.Atractylenolide-I Protects Human SH-SY5Y Cells from 1-Methyl-4-Phenylpyridinium-Induced Apoptotic Cell Death.p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism.p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration.MPP+-induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1.Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+-treated SH-SY5Y human dopaminergic cells.Proteasome-dependent degradation of cyclin D1 in 1-methyl-4-phenylpyridinium ion (MPP+)-induced cell cycle arrest.The MPTP Story.Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model.Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage.A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism.c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.Tp53 gene mediates distinct dopaminergic neuronal damage in different dopaminergic neurotoxicant models.Sulfuretin Attenuates MPP⁺-Induced Neurotoxicity through Akt/GSK3β and ERK Signaling Pathways.Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.ZFM1/SF1 mRNA in rat and gerbil brain after global ischaemia.Dopaminergic Neuron-Specific Deletion of p53 Gene Attenuates Methamphetamine Neurotoxicity.N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic CAtaxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.
P2860
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P2860
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity.
description
1996 nî lūn-bûn
@nan
1996 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@ast
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@en
type
label
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@ast
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@en
prefLabel
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@ast
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@en
P2093
P356
P1476
Dopamine neurons from transgen ...... ene resist MPTP neurotoxicity.
@en
P2093
P304
P356
10.1006/NEUR.1996.0031
P407
P577
1996-09-01T00:00:00Z