Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance. - Test2 - elhamkhani - TriplyDB

Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.

Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.

http://www.wikidata.org/entity/Q30477159

about

The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells DNA damage associated with mitosis and cytokinesis failure Cohesin is dispensable for centromere cohesion in human cells Dual role of topoisomerase II in centromere resolution and aurora B activity DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint The evolutionary origin of man can be traced in the layers of defunct ancestral alpha satellites flanking the active centromeres of human chromosomes Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.Mitotic catenation is monitored and resolved by a PKCε-regulated pathway H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue Haspin: a newly discovered regulator of mitotic chromosome behavior.PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture.STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure.The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation.A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.Investigating the Interplay between Sister Chromatid Cohesion and Homolog Pairing in Drosophila Nuclei The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells Differential requirements of a mitotic acetyltransferase in somatic and germ line cells.SUMO modification of DNA topoisomerase II: trying to get a CENse of it all Metnase mediates chromosome decatenation in acute leukemia cells.Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity Cohesin: a regulator of genome integrity and gene expression.Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes.Stressing mitosis to death.Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi.Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes.Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells.Protein phosphatase 2A and separase form a complex regulated by separase autocleavage.The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation.Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei.Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation.Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression.

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Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.

http://www.wikidata.org/entity/Q30477159

description

2006 nî lūn-bûn

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Molecular Biology of the Cell

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Coordinated requirements of hu ...... indle checkpoint surveillance.

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Mitsuhiro Yanagida

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Yusuke Toyoda

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P2860

Characterization of vertebrate cohesin complexes and their regulation in prophase

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome

Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B

Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts

Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line

A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1

Identification of a human mitotic checkpoint gene: hsMAD2

Precocious sister chromatid separation (PSCS) in Cornelia de Lange syndrome

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

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2287-2302

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10.1091/MBC.E05-11-1089

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5

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1446084

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