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Protein release through nonlethal oncotic pores as an alternative nonclassical secretory pathwaySynthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitorsMicrovesicle shedding and lysosomal repair fulfill divergent cellular needs during the repair of streptolysin O-induced plasmalemmal damageChlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular developmentCOPI complex is a regulator of lipid homeostasisIn vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compoundsLethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210In vitro screening for compounds that enhance human L1 mobilizationThe small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing.Evidence that mono-ADP-ribosylation of CtBP1/BARS regulates lipid storage.Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (Arf1) with potential for cancer therapy.The small molecule dispergo tubulates the endoplasmic reticulum and inhibits exportSmall-molecule screening and profiling by using automated microscopy.Sorting inhibitors (Sortins): Chemical compounds to study vacuolar sorting in ArabidopsisChemical substructures that enrich for biological activityNovel effects of Brefeldin A (BFA) in signaling through the insulin receptor (IR) pathway and regulating FoxO1-mediated transcription.At the crossroads of chemistry and cell biology: inhibiting membrane traffic by small molecules.Increasing the Content of High-Content Screening: An OverviewThe potential of high-content high-throughput microscopy in drug discovery.M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells.A conserved role for the ESCRT membrane budding complex in LINE retrotranspositionGolgicide A reveals essential roles for GBF1 in Golgi assembly and functionRafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER.One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine.Characterization of class I and II ADP-ribosylation factors (Arfs) in live cells: GDP-bound class II Arfs associate with the ER-Golgi intermediate compartment independently of GBF1.Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic.The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network.Intracellular trafficking and exocytosis of a multi-component siRNA nanocomplex.A novel small molecule regulator of guanine nucleotide exchange activity of the ADP-ribosylation factor and golgi membrane trafficking.Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition.The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells.Nitric oxide mediates activity-dependent plasticity of retinal bipolar cell output via S-nitrosylation.Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis.A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.The application of phenotypic high-throughput screening techniques to cardiovascular research.Inhibitors of the cellular trafficking of ricin.Golgi tubules: their structure, formation and role in intra-Golgi transport.Leishmania hijacking of the macrophage intracellular compartments.Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Exo1: a new chemical inhibitor of the exocytic pathway
@ast
Exo1: a new chemical inhibitor of the exocytic pathway
@en
type
label
Exo1: a new chemical inhibitor of the exocytic pathway
@ast
Exo1: a new chemical inhibitor of the exocytic pathway
@en
prefLabel
Exo1: a new chemical inhibitor of the exocytic pathway
@ast
Exo1: a new chemical inhibitor of the exocytic pathway
@en
P2093
P2860
P356
P1476
Exo1: a new chemical inhibitor of the exocytic pathway
@en
P2093
Ashutosh P Jadhav
Eric Macia
Michael Roth
Paul Melancon
Pierre Chardin
Timothy Mitchison
Tomas Kirchhausen
Troy K R Lasell
P2860
P304
P356
10.1073/PNAS.0631766100
P407
P577
2003-05-08T00:00:00Z