A two-step nucleotide-flipping mechanism enables kinetic discrimination of DNA lesions by AGT
about
CHARMM: the biomolecular simulation programFlipping of alkylated DNA damage bridges base and nucleotide excision repairEncounter and extrusion of an intrahelical lesion by a DNA repair enzymeEnzymatic transition states and dynamic motion in barrier crossing.Recent developments in methods for identifying reaction coordinates.O6-methylguanine induces altered proteins at the level of transcription in human cellsThe effect of a G:T mispair on the dynamics of DNADNA pol λ's extraordinary ability to stabilize misaligned DNA.Mapping L1 ligase ribozyme conformational switch.Understanding the kinetic mechanism of RNA single base pair formationReaction mechanism and reaction coordinates from the viewpoint of energy flowUsing the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA.The stochastic separatrix and the reaction coordinate for complex systems.Hidden Conformation Events in DNA Base Extrusions: A Generalized Ensemble Path Optimization and Equilibrium Simulation Study.Physics of protein-DNA interactions: mechanisms of facilitated target search.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.DNA repair by reversal of DNA damage.Effect of O6-alkylguanine-DNA alkyltransferase on genotoxicity of epihalohydrins.Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase.Base flip in DNA studied by molecular dynamics simulationsof differently-oxidized forms of methyl-CytosineReducing the cost of evaluating the committor by a fitting procedure.Thermodynamics of G x A mispairs in DNA: continuum electrostatic model.Site-specific covalent capture of human O6-alkylguanine-DNA-alkyltransferase using single-stranded intrastrand cross-linked DNA.Preserving correlations between trajectories for efficient path sampling.Steered transition path sampling.Identification of the protein folding transition state from molecular dynamics trajectories.Nonequilibrium umbrella sampling in spaces of many order parameters.O(6)-Alkylguanine DNA Alkyltransferase Repair Activity Towards Intrastrand Cross-Linked DNA is Influenced by the Internucleotide Linkage.Synthesis, Characterization, and Repair of a Flexible O(6) -2'-Deoxyguanosine-alkylene-O(6) -2'-deoxyguanosine Intrastrand Cross-Link.Base-flipping dynamics from an intrahelical to an extrahelical state exerted by thymine DNA glycosylase during DNA repair process.
P2860
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P2860
A two-step nucleotide-flipping mechanism enables kinetic discrimination of DNA lesions by AGT
description
2008 nî lūn-bûn
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2008 թուականի Մարտին հրատարակուած գիտական յօդուած
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2008 թվականի մարտին հրատարակված գիտական հոդված
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@ast
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@en
type
label
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@ast
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@en
prefLabel
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@ast
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@en
P2093
P2860
P356
P1476
A two-step nucleotide-flipping ...... mination of DNA lesions by AGT
@en
P2093
P2860
P304
P356
10.1073/PNAS.0708058105
P407
P577
2008-03-19T00:00:00Z