A mouse model of the human Fragile X syndrome I304N mutation. - Test2 - elhamkhani - TriplyDB

A mouse model of the human Fragile X syndrome I304N mutation.

A mouse model of the human Fragile X syndrome I304N mutation.

http://www.wikidata.org/entity/Q30484632

about

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism Fragile x syndrome Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.RNA protein interaction in neurons The FMRP regulon: from targets to disease convergence The unstable repeats--three evolving faces of neurological disease Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction Modeling Fragile X Syndrome Using Human Pluripotent Stem Cells Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish A Nondegenerate Code of Deleterious Variants in Mendelian Loci Contributes to Complex Disease Risk From FMRP function to potential therapies for fragile X syndrome.Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders Automated multi-day tracking of marked mice for the analysis of social behaviour Fragile X mental retardation protein regulates translation by binding directly to the ribosome Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome.Meeting at the crossroads: common mechanisms in Fragile X and Down syndrome Increasing our understanding of human cognition through the study of Fragile X Syndrome.A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia.Concise review: Fragile X proteins in stem cell maintenance and differentiation Programmed cell death is impaired in the developing brain of FMR1 mutants Behavioral profiles of mouse models for autism spectrum disorders.Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells.Defects in translational regulation contributing to human cognitive and behavioral disease.New perspectives on the biology of fragile X syndrome RNA-binding proteins involved in RNA localization and their implications in neuronal diseases.Cytoplasmic RNA-binding proteins and the control of complex brain function.Role of a redox-based methylation switch in mRNA life cycle (pre- and post-transcriptional maturation) and protein turnover: implications in neurological disorders.Fragile X mental retardation protein and synaptic plasticity The translation of translational control by FMRP: therapeutic targets for FXS.Fragile X syndrome: a preclinical review on metabotropic glutamate receptor 5 (mGluR5) antagonists and drug development.RNA binding proteins: a common denominator of neuronal function and dysfunction.Regulation of monocyte induced cell migration by the RNA binding protein, FXR1.Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation.Screening the Molecular Framework Underlying Local Dendritic mRNA Translation.Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions.A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome.Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

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A mouse model of the human Fragile X syndrome I304N mutation.

http://www.wikidata.org/entity/Q30484632

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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A mouse model of the human Fragile X syndrome I304N mutation.

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A mouse model of the human Fragile X syndrome I304N mutation.

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A mouse model of the human Fragile X syndrome I304N mutation.

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A mouse model of the human Fragile X syndrome I304N mutation.

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A mouse model of the human Fragile X syndrome I304N mutation.

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A mouse model of the human Fragile X syndrome I304N mutation.

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JOURNAL.PGEN.1000758

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A mouse model of the human Fragile X syndrome I304N mutation.

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P2093

Corinne M Spencer

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Elena D Nosyreva

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Elizabeth F Stone

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Jennifer C Darnell

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Julie B Zang

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Kimberly M Huber

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Kiran Musunuru

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Lisa A Yuva-Paylor

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Richard Paylor

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P2860

A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome

Correction of fragile X syndrome in mice.

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction

The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2

High frequency of neurexin 1beta signal peptide structural variants in patients with autism

Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Altered synaptic plasticity in a mouse model of fragile X mental retardation

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