Gap-junction channels dysfunction in deafness and hearing loss.
about
Diseases associated with leaky hemichannelsFunctional analysis and regulation of purified connexin hemichannelsGap junctionsMotifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensingKeratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43.Connexins and Pannexins: New Insights into Microglial Functions and DysfunctionsBioinformatic Analysis of GJB2 Gene Missense Mutations.ACEMg Diet Supplement Modifies Progression of Hereditary Deafness.Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells.Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.Viral vector tropism for supporting cells in the developing murine cochlea.BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice.Mouse otocyst transuterine gene transfer restores hearing in mice with connexin 30 deletion-associated hearing loss.Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegansPost-translational modifications of connexin26 revealed by mass spectrometry.Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels.Functional hemichannels formed by human connexin 26 expressed in bacteriaDifferent domains are critical for oligomerization compatibility of different connexins.Connexinopathies: a structural and functional glimpseBiological role of connexin intercellular channels and hemichannelsCritical role of the first transmembrane domain of Cx26 in regulating oligomerization and functionPermeation of calcium through purified connexin 26 hemichannels.Role of connexins in infantile hemangiomasInsights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).Construction of a DNA chip for screening of genetic hearing loss.Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models.Mechanism of gating by calcium in connexin hemichannelsConnexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea.Ultrastructural pathological changes in the cochlear cells of connexin 26 conditional knockout mice.A Cell-Based Assay to Assess Hemichannel FunctionKey functions for gap junctions in skin and hearing.Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome.Connexins: key mediators of endocrine function.Modulation of gap junction channels and hemichannels by growth factors.Transient downregulation of microRNA-206 protects alkali burn injury in mouse cornea by regulating connexin 43.Permeation pathway of homomeric connexin 26 and connexin 30 channels investigated by molecular dynamics.Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.Understanding of the molecular evolution of deafness-associated pathogenic mutations of connexin 26.Characterization of a novel water pocket inside the human Cx26 hemichannel structure.Structural studies of N-terminal mutants of Connexin 26 and Connexin 32 using (1)H NMR spectroscopy.
P2860
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P2860
Gap-junction channels dysfunction in deafness and hearing loss.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Gap-junction channels dysfunction in deafness and hearing loss.
@ast
Gap-junction channels dysfunction in deafness and hearing loss.
@en
type
label
Gap-junction channels dysfunction in deafness and hearing loss.
@ast
Gap-junction channels dysfunction in deafness and hearing loss.
@en
prefLabel
Gap-junction channels dysfunction in deafness and hearing loss.
@ast
Gap-junction channels dysfunction in deafness and hearing loss.
@en
P2093
P2860
P356
P1476
Gap-junction channels dysfunction in deafness and hearing loss.
@en
P2093
Agustín D Martínez
Bruce Nicholson
Jaime Maripillan
Rodrigo Acuña
Vania Figueroa
P2860
P304
P356
10.1089/ARS.2008.2138
P577
2009-02-01T00:00:00Z