Gap-junction channels dysfunction in deafness and hearing loss. - Test2 - elhamkhani - TriplyDB

Gap-junction channels dysfunction in deafness and hearing loss.

Gap-junction channels dysfunction in deafness and hearing loss.

http://www.wikidata.org/entity/Q30490087

about

Diseases associated with leaky hemichannels Functional analysis and regulation of purified connexin hemichannels Gap junctions Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43.Connexins and Pannexins: New Insights into Microglial Functions and Dysfunctions Bioinformatic Analysis of GJB2 Gene Missense Mutations.ACEMg Diet Supplement Modifies Progression of Hereditary Deafness.Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells.Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.Viral vector tropism for supporting cells in the developing murine cochlea.BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice.Mouse otocyst transuterine gene transfer restores hearing in mice with connexin 30 deletion-associated hearing loss.Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans Post-translational modifications of connexin26 revealed by mass spectrometry.Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels.Functional hemichannels formed by human connexin 26 expressed in bacteria Different domains are critical for oligomerization compatibility of different connexins.Connexinopathies: a structural and functional glimpse Biological role of connexin intercellular channels and hemichannels Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function Permeation of calcium through purified connexin 26 hemichannels.Role of connexins in infantile hemangiomas Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).Construction of a DNA chip for screening of genetic hearing loss.Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models.Mechanism of gating by calcium in connexin hemichannels Connexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea.Ultrastructural pathological changes in the cochlear cells of connexin 26 conditional knockout mice.A Cell-Based Assay to Assess Hemichannel Function Key functions for gap junctions in skin and hearing.Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome.Connexins: key mediators of endocrine function.Modulation of gap junction channels and hemichannels by growth factors.Transient downregulation of microRNA-206 protects alkali burn injury in mouse cornea by regulating connexin 43.Permeation pathway of homomeric connexin 26 and connexin 30 channels investigated by molecular dynamics.Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.Understanding of the molecular evolution of deafness-associated pathogenic mutations of connexin 26.Characterization of a novel water pocket inside the human Cx26 hemichannel structure.Structural studies of N-terminal mutants of Connexin 26 and Connexin 32 using (1)H NMR spectroscopy.

P2860

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P2860

Gap-junction channels dysfunction in deafness and hearing loss.

http://www.wikidata.org/entity/Q30490087

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2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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name

Gap-junction channels dysfunction in deafness and hearing loss.

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Gap-junction channels dysfunction in deafness and hearing loss.

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type

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Gap-junction channels dysfunction in deafness and hearing loss.

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Gap-junction channels dysfunction in deafness and hearing loss.

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Gap-junction channels dysfunction in deafness and hearing loss.

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Gap-junction channels dysfunction in deafness and hearing loss.

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Antioxidants & Redox Signaling

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Gap-junction channels dysfunction in deafness and hearing loss.

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Agustín D Martínez

http://www.w3.org/2001/XMLSchema#string

Bruce Nicholson

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Jaime Maripillan

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Rodrigo Acuña

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Vania Figueroa

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P2860

Connexin 26 mutations in hereditary non-syndromic sensorineural deafness

Mutations in connexin31 underlie recessive as well as dominant non-syndromic hearing loss

Gap junction systems in the mammalian cochlea

Mutations in GJB6 cause nonsyndromic autosomal dominant deafness at DFNA3 locus

Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness

K+ cycling and the endocochlear potential

New roles for astrocytes: gap junction hemichannels have something to communicate

Functional studies of human skin disease- and deafness-associated connexin 30 mutations

Defective trafficking and cell death is characteristic of skin disease-associated connexin 31 mutations

Human connexin26 and connexin30 form functional heteromeric and heterotypic channels

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2

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11

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